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Aug 12, 2002 - ovalbumin and of i.n. delivered CTB-producing BCG induced a long-lasting ... The M. bovis BCG vaccine strain 1173P2 (World Health.
products and external environmental factors [23]. Drug-induced lupus erythematosus (DILE) is defined as a lupus-like disease that is temporally related to drug ...
recognize and lyse HBx-positive hepatoma cells in vitro. Both CD8+ T and CD4+ T lymphocytes are involved in the antitumor immune response induced by the ...
potent antitumor immunity against antigens encapsulated in it. Especially, the present ... of the T-cell receptor (3). Both CD4+ and CD8+ T cells have been shown.
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Feb 21, 2010 - were collected and analyzed by using CXP software (Beckman ...... Seo, J. Y., S. Y. Seong, B. Y. Ahn, I. C. Kwon, H. Chung, and S. Y. Jeong.
Lei ZHANG, Yan-wen WANG, Zhi-qiang LUâ â¡. (Key Laboratory of Plant Protection Resources and Pest Management, Ministry of Education,. Northwest A&F ...
Jul 31, 2012 - Immunization with the HA DNA Vaccines of Two. Antigenically ...... (Sigma, St. Louis, MO), and CD8+ T cell responses were determined by ..... Jensen KE, Davenport FM, Hennessy AV, Francis T Jr (1956) Characterization.
May 11, 2012 - Vaccine Co-Expressing Swine IL-18 and Membrane Protein of. Porcine ..... Tong, G.Z.; Zhou, Y.J.; Hao, X.F.; Tian, Z.J.; An, T.Q.; Qiu, H.J. Highly ...
Jul 22, 2015 - determine the cross-protective potential of available vaccines and optimise strategic ...... Seo SH, Pei J, Briles WE, Dzielawa J, Collisson EW.
The intestinal mucosa is the largest sur- face exposed by the .... mucosal IgA responses to the antigen (15), a ... ance and mucosal immunology. Annals of.
by Gene Gun delivery of the 47-kDa domain of SERA elicited a significantly higher serum ..... 32-fold higher than the highest titer that was generated by i.m..
Apr 13, 2015 - hepatitis A and E infection simultaneously, a combined mucosal ... Subsequent experiments in BALB/c mice demonstrated that tuftsin en- .... The HAV VP1 epitope lies between amino acids (aa) 1â221 [15], ... and enzyme-linked immunospo
Aug 30, 2016 - Read online: Scan this QR code with your smart phone or mobile device to read online. Onderstepoort Journal of Veterinary Research.
Mar 5, 2017 - vaccines against this virus, with at least eight entering clinical trials in 2014â16.1 ... stomatitis virus genetically modified to express Ebola.
Jan 7, 2014 - A, González Y and Dueñas-Carrera S designed the research;. Amador-Cañizares ...... Susana Mir, Isabel González, Alejandrina Piña, Georgina.
the genus Myxobolus as being responsible of the anti- genic mimicry is not shown ... Myxozoma cerebralis which mimic tissue antigens of rain- bow trout (Salmo ...
of DNA Vaccines That Express Immunogenic Regions of the ... responses were detected following DNA vaccination with the N-terminal domain of SERA, ...
Jun 15, 2010 - DNA vaccines have undergone important enhancements in their design, formulation, and delivery process. Past literature supports that DNA ...
Jan 4, 1999 - ... as optical density (OD) indices (OD for the bovine PPD sam- ..... Vilcek, J., A. Klion, D. Henriksen-DeStefano, A. Zemtov, D. M. Davidson, M.
Feb 14, 2014 ... Analysis of immune responses induced by avian pathogenic Escherichia coli
infection in turkeys and their association with resistance to ...
Dec 16, 2016 - that the recombinant Bacillus subtilis B.S.-HA could be sampled by ..... R. Genetic system constructed to overproduce and secrete proinsulin in ...
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OPEN
received: 21 June 2016 accepted: 17 October 2016 Published: 16 December 2016
Immune Responses Induced by Recombinant Bacillus Subtilis Expressing the Hemagglutinin Protein of H5N1 in chickens Chunxiao Mou, Liqi Zhu, Jingjing Yang, Wenwen Xu, Xiaoying Cheng & Qian Yang To develop an effective, safe, and convenient vaccine for the prevention of highly pathogenic avian influenza (HPAI) H5N1, we have constructed a recombinant Bacillus subtilis strain (B.S.-HA) expressing the hemagglutinin (HA) protein. Then we evaluated the immune function in chicken bone marrow derived dendritic cells (BM-DCs), and the immune response after oral immunization. Our results show that the recombinant Bacillus subtilis B.S.-HA could be sampled by BM-DCs in vitro and increase the BM-DCs major histocompatibility complex (MHC) II phenotype. The weight, height of the small intestine villus, and lymphoid tissue area of the ileum increased significantly in B.S.-HA immunized chickens (P