Impact of preoperative use of P2Y12 receptor ... - SAGE Journals

1 downloads 0 Views 813KB Size Report
DOI: 10.1177/2048872615585516 journals.sagepub.com/home/acc. Impact of preoperative use of. P2Y12 receptor inhibitors on clinical outcomes in cardiac and ...
585516 research-article2015

ACC0010.1177/2048872615585516European Heart Journal: Acute Cardiovascular CareSiller-Matula et al.

EUROPEAN SOCIETY OF CARDIOLOGY ®

Review

Impact of preoperative use of P2Y12 receptor inhibitors on clinical outcomes in cardiac and non-cardiac surgery: A systematic review and meta-analysis

European Heart Journal: Acute Cardiovascular Care 1­–18 © The European Society of Cardiology 2015 Reprints and permissions: sagepub.co.uk/journalsPermissions.nav DOI: 10.1177/2048872615585516 acc.sagepub.com

Jolanta M Siller-Matula1, Alexandra Petre1, Georg Delle-Karth1, Kurt Huber2, Cihan Ay3, Marie Lordkipanidzé4, Raffaele De Caterina5, Philippe Kolh6, Elisabeth Mahla7 and Bernard J Gersh8

Abstract Objective: To review systematically the evidence and perform a meta-analysis of benefits and risks associated with use of P2Y12 receptor inhibitors in coronary artery bypass graft-, non-cardiac- and device surgery. Data selection and analysis: We performed a meta-analysis of published studies. Patients with preoperative use of clopidogrel, ticagrelor or prasugrel (late discontinuation: