Impact of source data on the interpretation of contrast-enhanced ...

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Apr 23, 2014 - Queen Margaret Hospital, Whitefield Road, Dunfermline KY12 OSU, UK. 5School of ... Malcolm PN, Craven P, Klass D: Pitfalls and artefacts in ...
Lewis et al. BMC Research Notes 2014, 7:263 http://www.biomedcentral.com/1756-0500/7/263

RESEARCH ARTICLE

Open Access

Impact of source data on the interpretation of contrast-enhanced magnetic resonance angiography of the lower limbs Mark Lewis1*, Madhavi Venumbaka2, Kevin Gill3, James Cannon4, Allan Clark5, Andoni P Toms1 and Paul N Malcolm1

Abstract Background: The primary purpose of this study is to examine whether use of source data is effective in increasing the number of arterial segments that can be interpreted from maximum intensity projections of lower limb MR angiograms. Correlation between sites of arterial disease and venous contamination was also measured. Interpretation of source data is performed routinely by radiologists, but the value of this has not been well studied with randomized studies. Results: The proportion of segments visible above the knee was 87% using maximal intensity projection alone (MIP) and 88% when the MIP was combined with source data. The proportions were 67% for MIP and 72% for MIP plus source data below the knee. There was substantial agreement between presence of arterial disease and venous contamination in the calf and thigh. Conclusion: The use of source data increases the number of assessable segments, but not individuals, by a statistically significant but small amount (1.2%, p

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