surgery, intraoperative transfusion of only one to two units of packed red blood cells (PRBC) has been shown to significantly elevate the risk for surgical-site ...
in vivo 31: 251-258 (2017) doi:10.21873/invivo.11053
Improvement of Perioperative Outcomes in Major Gynecological and Gynecologic–Oncological Surgery with Hemostatic Gelatin–Thrombin Matrix RAFAŁ WATROWSKI1, CHRISTOPH JÄGER1 and JOHANNES FORSTER2
Departments of 1Gynecology and Obstetrics, and 2Pediatrics, St. Josefskrankenhaus, Teaching Hospital of the University of Freiburg, Freiburg, Germany
Abstract. Aim: To assess the impact of the use of intraoperative hemostatic gelatin-thrombin matrix (HM) (Floseal®, Baxter Healthcare) on transfusion rates and short-term perioperative outcomes in gynecological surgery. Patients and Methods: In this retrospective, single-center study, we evaluated data of 215 patients (83 cases and 132 controls) undergoing extensive gynecological surgery (e.g. oncological procedures) with and without intraoperative HM application. Results: Cases and controls did not differ according to age, preoperative hemoglobin (Hb) concentration, and Hb or C-reactive protein (CRP) levels at discharge. Patients receiving HM had significantly reduced operative (168 vs. 199 min, p=0.02) and hospitalization (9 vs. 14 days, p
