In vitro and in vivo antifungal activity of cetrimide
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In vitro and in vivo antifungal activity of cetrimide
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Original article
In vitro and in vivo antifungal activity of cetrimide (cetyltrimethyl ammonium bromide) against fungal keratitis caused by Fusarium solani Yehia A.-G. Mahmoud Botany Department, Mycology Research Lab., Faculty of Science, Tanta University, Tanta, Egypt
Summary
Mycotic keratitis is a devastating eye infection acquired after eye injury. Cetrimide at 15 and 20 mg ml)1 produced no surviving Fusarium solani growth with minimal inhibitory concentration value of 0.10 mg ml)1. Topical administration of three drops (0.3 ml) of cetrimide aqueous solution of 10 mg ml)1 at pH 6.4 three times daily succeeded to cure human severe resistant F. solani keratitis in a time course of
