Background: Growth hormone (GH), Insulin-like growth factor-I (somatomedine, IGF-I) and gastrin seem to play a significant role in cell proliferation in mamalian ...
Before identifying means to treat acromegaly, ... GH-secreting pituitary tumors and acromegaly. ..... in infancy: a survey of possible disorders and guidelines for.
Nov 13, 2007 - M.M. Furtado5, N.M. Torres5, P.S.R. Mattos3, P. Viau8, T.F.G. Lima2 and R.G. ... lishment of an international management plan for the de-.
Growth hormone (GH) is secreted episodically, with low or undetectable daytime .... The median, inter-quartile ranges and 95% confidence limits of fasting CH ...
SUMMARY. Objective. To determine the serum levels of soluble vascular cell adhesion molecule-1 (sVCAM-1) and soluble E-selectin. (sE-selectin) in patients ...
Microscopic polyangiitis (MPA) was considered as small vessel vasculitis ... Keywords: macrophage migration inhibitory factor, systemic vasculitis, microscopic.
endothelial leakage syndrome, and veno-occlusive disease are major complications of bone ..... cells might result in damage of small hepatic venules, which.
Serum Levels of Soluble P-Selectin Are Increased and Associated With Disease Activity in Patients. With Behc¸et's Syndrome. Yusuf Turkoz,1 Cem Evereklioglu ...
The subjects were 162 normal children, aged 1 month to 20 yr; 12 patients ..... 1. Baumann G. 1991 Growth hormone heterogeneity: genes, isohormones, vari-.
Jul 22, 2017 - Improvement of 25(OH)D3 by Long-Term Bisphosphonate. 241. Tohoku J. ..... Park, H.M., Shin, C.S., Choi, S.H., Park, J.S., et al. (2014). Efficacy ...
Increased serum interleukin-6 levels in patients with hidradenitis suppurativa. Haoxiang Xu1,2, Xuemin Xiao3, Yanyan He1,2, Xiaofeng Zhang1,2, Chengrang ...
32 Karagiannis, S. N., King, R. H. and Thomas, P. K. (1997) Colocalisation of ... 38 Elleman, T. C., Frenkel, M. J., Hoyne, P. A., McKern, N. M., Cosgrove, L., ...
Objectives. Necrotizing vasculitis and granuloma formation are the predominant features of Wegener's .... piratory failure, cerebral vasculitis, or acute abdominal.
cancer cells, DJ-1 is known as an oncogene, which reacts with activated Ras [4] ... colorectal cancer is increased in patients with acromegaly ...... wars, one front.
VEGF in quail resulted in hypervascularity and hyper- the disease. A majority of WG patients have classic antineutrophil cytoplasmic antibodies (c-ANCA) [2],.
Goteborg; and the Department of Pediatrics, Northern Alusborg Hospital (H.F.), S-461 85 Trollhattan, .... Leptin was measured by RIA (Linco Research, Inc., St. Charles, MO). ..... Beshyah SA, Rutherford OM, Thomas E, Murphy M, Johnston DG.
microplate, and then 80 µL of the immunoreagent cover was added to each well and covered with an adhesive foil. After incubation using an microplate shaker ...
As known multiple sclerosis (MS) is a ... some inflammatory markers in MS patients and their relationships with clinical ..... 320.5 083.0·513.0) 300.0 049.0-937.0).
Sep 8, 2016 - with rheumatoid arthritis (RA), systemic lupus erythematosus (SLE) and primary ... peptides (anti-CCP), anti-GRP78, and anti-CarGRP78 were ...
JOHN C. SCARLETT, AND WILLIAM F. BENNETT. Division of Endocrinology and Metabolism (M.O.T., M.S., S.S.P.), Department of Medicine, and. National ...
Serum levels of IGF-I, IGF-II and IGFBP-3 were measured by ELISA. ... I:IGFBP-3 molar ratio (0.094 versus 0.137, p < 0.001) were observed among cancer cases, ...
Mar 18, 2015 - stable Coronary Syndromes (OPUS-TIMI 16) trial. Other two ..... Zhang B, Wang P, Chen CG, He QQ, Zhuo SY, Chen YM, et al. Validation of an ...
May 22, 2015 - 4 [email protected]. Abstract. Background. Despite observational evidence from epidemiological and clinical studies associating ...
Jun 11, 2018 - A systematic review. J Am Geriatr Soc 2012;60:1487â. 1492. 3. Puts MTE. Frailty: Biological risk factors, negative con- sequences and quality of ...
Increased fasting serum levels of growth hormone and gastrin in patients with gastric and large bowel cancer. J.K. Triantafillidis1, V. Govosdis1, Evangelia ...
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ANNALS OF GASTROENTEROLOGY J.K. TRIANTAFILLIDIS, 2002, 15(1):72-77 et al
Original article
Increased fasting serum levels of growth hormone and gastrin in patients with gastric and large bowel cancer J.K. Triantafillidis1, V. Govosdis1, Evangelia Konstandellou2, P. Cheracakis1, C. Barbatzas1, D. Tzourmakliotis3, Maria Sklavaina1
SUMMARY Background: Growth hormone (GH), Insulin-like growth factor-I (somatomedine, IGF-I) and gastrin seem to play a significant role in cell proliferation in mamalian and rat cells. The role of these factors in the etiology of gastric and large bowel cancer has not been completely elucitated. The aim of this study was to concurrently estimate the levels of GH, IGF-I and gastrin in a group of patients with gastric and colorectal cancer and to compare the results with those of a group of normal controls. Patients and Methods: In 33 consequtive patients with gastric (16 patients) and large bowel (17 patients) cancer, the serum levels of GH, IGF-I and gastrin were measured by radioimmunoassay. Fiftyfour normal people served as controls. Results: Significantly higher levels of serum GH (3.16±3.12 ng/ml in gastric cancer patients vs 3.01±2.91 ng/ml in colorectal cancer patients vs 0.69±1.60 ng/ml in normal controls, adjusted P