Jan 13, 2018 - Xiang Qian Lao,1,2 Han-Bing Deng,1 Xudong Liu,1 Ta-Chien Chan,3 Zilong Zhang,1. Ly-yun Chang,4,5 Eng-Kiong Yeoh,1 Tony Tam,6 Martin ...
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BJSM Online First, published on January 13, 2018 as 10.1136/bjsports-2017-098199 Original article
Increased leisure-time physical activity associated with lower onset of diabetes in 44 828 adults with impaired fasting glucose: a population-based prospective cohort study Xiang Qian Lao,1,2 Han-Bing Deng,1 Xudong Liu,1 Ta-Chien Chan,3 Zilong Zhang,1 Ly-yun Chang,4,5 Eng-Kiong Yeoh,1 Tony Tam,6 Martin Chi Sang Wong,1 G Neil Thomas7 Abstract Aims To evaluate the effects of habitual leisure-time physical activity (LTPA) on incident type 2 diabetes in a prospective cohort of Chinese adults with impaired fasting glucose (IFG). 1 Jockey Club School of Public Methods 44 828 Chinese adults aged 20–80 years Health and Primary Care, with newly detected IFG but free from cardiovascular Faculty of Medicine, The Chinese and cerebrovascular disease were recruited and followed University of Hong Kong, Hong up from 1996 to 2014. Incident type 2 diabetes was Kong 2 Shenzhen Research Institute, identified by fasting plasma glucose ≥7 mmol/L. The the Chinese University of Hong participants were classified into four categories based on Kong, Shenzhen, China 3 Research Center for Humanities their self-reported weekly LTPA: inactive, low, moderate, or high. Hazard ratios (HRs) and population attributable and Social Sciences, Academia Sinica, Taipei, Taiwan fractions (PAFs) were estimated with adjustment for 4 Institute of Sociology, established diabetic risk factor. Academia Sinica, Taipei, Taiwan Results After 214 148 person-years of follow-up, 5 MJ Group, MJ Health Research we observed an inverse dose–response relationship Foundation, Taipei, Taiwan 6 between LTPA and diabetes risk. Compared with inactive Department of Sociology, The Chinese University of Hong participants, diabetes risk in individuals reporting low, Kong, Hong Kong moderate and high volume LTPA were reduced by 12% 7 Institute for Applied Health (HR 0.88, 95% CI 0.80 to 0.99; P=0.015), 20% (HR Research, College of Medical 0.80, 95% CI 0.71 to 0.90; P
