Abstract. Polycystic ovary syndrome (PCOS) occurs in 5-10% of premenopausal women. Studies suggest that PCOS is associated with increased risk of ...
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Annals of Clinical & Laboratory Science, vol. 36, no.3, 2006
Increased Serum Neopterin Levels in Women with Polycystic Ovary Syndrome
Burcu Barutcuoglu,1 A. Erkin Bozdemir,1 Didem Dereli,2 Zuhal Parildar,1 M. Isil Mutaf,1 Dilek Ozmen,1 and Oya Bayindir1 Departments of 1Clinical Biochemistry and 2Internal Medicine, Ege University Medical School, Izmir, Turkey Abstract. Polycystic ovary syndrome (PCOS) occurs in 5-10% of premenopausal women. Studies suggest that PCOS is associated with increased risk of coronary heart disease (CHD). To investigate this relationship, 15 PCOS women (group 1) and 10 healthy women (group 2) were studied. Blood leukocyte counts (white blood cells, WBC) and serum levels of total cholesterol, HDL-cholesterol, LDL-cholesterol, sensitive Creactive protein (sCRP), and neopterin were measured in the 2 groups. There were no significant differences in serum total cholesterol, HDL-cholesterol, or LDL-cholesterol concentrations between groups 1 and 2. Blood WBC counts and serum levels of neopterin and sCRP were significantly higher in group 1 than group 2. The median (min-max) levels were: WBC, group 1: 8.05 (5.10-9.70) cells x 109/L, group 2: 6.25 (4.70-9.70) cells x 109/L (p
