Advances in Microbiology, 2014, 4, 627-643 Published Online August 2014 in SciRes. http://www.scirp.org/journal/aim http://dx.doi.org/10.4236/aim.2014.410069
Insights into Pneumococcal Pathogenesis and Antibiotic Resistance Eric S. Donkor1, Ebenezer V. Badoe2 1
Department of Microbiology, College of Health Sciences, University of Ghana Medical School, Accra, Ghana Department of Child Health, College of Health Sciences, University of Ghana Medical School, Accra, Ghana Email:
[email protected]
2
Received 10 March 2014; revised 22 April 2014; accepted 26 May 2014 Copyright © 2014 by authors and Scientific Research Publishing Inc. This work is licensed under the Creative Commons Attribution International License (CC BY). http://creativecommons.org/licenses/by/4.0/
Abstract Since its discovery in 1891, the pneumococcus has been one of the most extensively studied microbes, and was involved in several historical findings such as the discovery of genetic material that was later shown to be DNA. The pneumococcus is part of the normal bacterial flora of the nasopharynx, but can on occasions progress to sterile sites of the body and cause invasive diseases. There are about one million new invasive pneumococcal infections every year, majority of which occur in the developing world where children
