International Electronic Journal of Medicine

International Electronic Journal of Medicine (IEJM) October 2011; Volume 1, Issue 1, Pages: 1-2

International Electronic Journal of Medicine Hamidreza Mahboobi 1, 2, Mohammad Esmaeil Shahrzad 3, 4 1234-

Student Research Committee, Hormozgan University of Medical Sciences (HUMS), Bandar Abbas, Iran. Payame Noor University (PNU), Iran. Fertility and Infertility Research Center, Hormozgan University of Medical Sciences, Bandar Abbas, Iran Behavioural and Neuroscience Research Center, Hormozgan University of Medical Sciences, Bandar Abbas, Iran

Please Cite This paper as: Mahboobi H, Shahrzad ME. International Electronic Journal of Medicine. Int Elec J Med 2011; 1(1): 1-2 International Electronic Journal of Medicine (IEJM) is an open access electronic journal that covers all aspects of medicine and medical sciences. We invite authors from all over the world to send their manuscripts to IEJM. Manuscripts submitted to IEJM go through a peer review process before publication in IEJM. We will ask our reviewers to finish the papers’ review within two weeks. Authors are requested to prepare their manuscripts according to the instructions provided for the authors to facilitate the review process. Each paper will be reviewed at least by two external reviewers and the final decision is made by the Editor-in-Chief based on the reviewer's comments. IEJM considers publishing original papers, Review articles, Case Reports, Short Communications and Letters to the Editors. IEJM will add other formats to this list in future if it was necessary. IEJM will continue its way towards publication of high quality and high impact scientific papers in the field of medicine. Our journal readers also have the possibility of free access to the full texts of all published articles. We invite all who are interested to contribute to our journal to fill our reviewer application forms on the website and send it to us via email. We know our journal will not succeed without your help and contribution. Development of the internet has changed many aspects of medicine and medical sciences (1). Evidence-Based Medicine is based on accessing updated medical evidence and the possibility of their critical appraisal (2). Electronic and online journals are rapidly developing and will play an important role in the future of EBM. Although EBM isn’t enough for current practice of medicine, it is still one of the best ways of practicing medicine (3, 4). Electronic journals can help EBM by providing the access to online peer reviewed medical evidence.

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Corresponding Author Hamidreza Mahboobi Student Research Committee, Hormozgan University of Medical Sciences (HUMS), Bandar Abbas, Iran. [email protected] Tel: 0098-9364300250

Int Elec J Med 2011; 1(1):1-2

International Electronic Journal of Medicine (IEJM) October 2011; Volume 1, Issue 1, Pages: 1-2 IEJM is committed to providing high quality, free online peer reviewed paper for researchers and physicians. We know we have a long way to achieve this goal, but we hope that with your contribution to IEJM, we will be able to accomplish this aim. References: 1. Marcinkiewicz M. Mahboobi H. The Impact of the internet on the Doctor-Patient Relationship. Australas Med J 2009;1(5):1-6.

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2. Mahboobi H, Sharma A, Khorgoei T, Jahanshahi KA, Cottrell E. Evidence-Based Medicine for Medical Students. Australas Med J 2010; 1(3):190-193. 3. Mahboobi HR, Mansoori F, Jahanshahi KA, Khorgoei T. Have we something to replace evidence based medicine?. An Card Anaesth 2011;14(3): 246. 4. Mahboobi HR, Parhiz AA, Jahanshahi KA, Khorgoei T. current form of randomized controlled trials. Ann Pediatr Card 2011; 4(1):90.

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Pathologic findings of patients with breast cancer in Bandarabbas (southern Iran) during 2002-2010 Abbas Rahimi 1, Elham Kazemi 1, Ebrahim Khajeh 2, Hamidreza Mahboobi 3, 4, Asal Arab 5, Tahereh Khorgoei 6, 7, Fatemeh Hafezipour 6, 7 1234567-

Assistant Professor, Hormozgan University of Medical Sciences(HUMS), Iran Infections & Tropical Disease Research Center, Hormozgan University of Medical Sciences (HUMS), Iran Student Committee, Education Development Center (EDC), Hormozgan University of Medical Sciences(HUMS), Iran Payame Noor University (PNU), Iran Behavioural and Neurosciences Research Center, Hormozgan University of Medical Sciences(HUMS), Iran Hormozgan Cardiovascular Disease Research Center, Hormozgan University of Medical Sciences(HUMS), Iran Hormozgan Fertility & Infertility Research Center, Hormozgan University of Medical Sciences(HUMS), Iran

Please cite this paper as: Rahimi A, Kazemi E, Khajeh E, Mahboobi HR, Arab A, Khorgoei T, Hafezipour F. Pathologic findings of patients with breast cancer in Bandarabbas (southern Iran) during 2002-2010. Int Elec J Med 2011; 1(1): 3-6 Corresponding author: Hamidreza Mahboobi, Student Committee, Education Development Center (EDC), Hormozgan University of Medical Sciences (HUMS), Iran, Tel: +98.9364300250. Email: [email protected]

ABSTRCT Introduction: Breast cancer is the most common cause of Cancer-related death among women. The aim of this study was to assess the pathologic findings of patients with breast cancer who were referred to the pathology ward in Bandarabbas during 2002 to 2010. Methods and Materials: In this descriptive study in 2010, all patients with breast cancer who were referred to the pathology ward of Bandarabbas during 2002 to 2010 were included. Data was obtained using patients’ records in the pathology ward and was collected by using a previously structured checklist including demographics such as age, sex as well as information regarding histology, histology grade, size and location of the tumor. Data was analyzed after collection using SPSS 13.0 for Windows software. Results: Among the patients 73 (92.4%) were female. The mean age of the patients in our study was 52.38±14.27 years. Thirty (44.8%) were infiltrative ductal carcinoma and 26 (38.8%) were invasive ductal carcinoma. Histologic grade I was found in 10 (20.8%) patients, grade II in 24 (50%) and grade III in 14 (29.2%) patients. Skin was involved in 11(13.9%) cases. Vascular and neural involvement was seen in 16 (20.3%) and 6 (7.6%) patients respectively. Regional lymph nodes were involved in 32 (40.5%) of the patients. Far metastasis was seen only in 1 (1.3%) patient. Conclusions: Referral of the patients in late stages of their disease which is associated with vascular, skin and nipple involvement and also regional lymph node involvement indicated a lack of enough knowledge about the disease. Keywords: Breast Neoplasms, Ductal, Carcinoma

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Int Elec J Med 2011; 1(1):3-6

International Electronic Journal of Medicine (IEJM) October 2011; Volume 1, Issue 1, Pages: 3-6 Introduction: Breast cancer is one of the most prevalent cancers (1) and is the most common cause of Cancer-related death among women (2). The incidence of breast cancer is 22 in 100000 in Iran (3). The average age of patients diagnosed with this disease in Iran is 10 years younger than other countries (4). Early diagnosis and treatment affects the prognosis of these patients (5). Despite the progress in treatment options for these patients, the most important predictive factor of the prognosis of these patients is the pathology report of the tissues taken at the time of the diagnosis and the patients' mortality depends on the stage of the tumor at the beginning of the diagnosis (6). Previous studies in Iran showed that more than 85% of breast cancer patients are detected in Grade II or III of the disease (6). Also, this disease is more frequent in 31 to 40 year old patients. Although it has been shown that in some cases the pathology reports are not complete (1), the pathologic findings reveal the stage of the disease at the beginning of the diagnosis. Late referral of patients in higher stages of the disease causes bad prognosis even with an accurate diagnosis and suitable treatment and it is associated with a great mortality rate. The pathology report at the beginning of the diagnosis shows the prevalence of late referral (8). The aim of this study is to assess the pathologic findings of patients with breast cancer who were referred to the pathology ward of Shahid Mohammadi hospital during 2002 to 2010. Methods:

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This descriptive study was conducted in Bandarabbas (southern Iran) in 2010. All patients with breast cancer who were referred to the pathology ward in Bandarabbas during 2002 to 2010 were included in our study. After exclusion of the patients with incomplete records, 79 patients were enrolled in our study. Bandarabbas is located in the Hormozgan province in southern Iran and is the capital city of Hormozgan. Data was obtained using patients’ records in the pathology ward and was collected using a previously structured checklist including demographics such as age and sex and also information regarding the histology, the histology grade, the size and the location of the tumor. Data was analyzed by SPSS 13.0 software for Windows. Descriptive statistics such as frequency was used for sex, histology grade (I, II, III), tumor location and vascular, neural, skin or nipple involvement. For quantitive variables such as age and tumor size, mean and standard deviation were assumed. Results: Among all the patients, 6 (7.6%) were male and 73 (92.4%) were female. The mean age of the patients in our study was 52.38±14.27 years. The mean tumor size was 80.48±90.89 mm2. All the histology types were ductal carcinoma. Thirty (44.8%) were infiltrative ductal carcinoma and 26 (38.8%) were invasive ductal carcinoma. Histologic grade I was found in 10 (20.8%) patients, grade II in 24 (50%) and grade III in 14 (29.2%) patients. The tumor was in the right breast in 13 (32.5%) patients and in the left breast in 26 (65%) patients and in both breasts in 1 (2.5%) patient.

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International Electronic Journal of Medicine (IEJM) October 2011; Volume 1, Issue 1, Pages: 3-6 Deep resected margin was seen in 11 (13.9%). Nipple involvement was seen in 11 (13.9%). Also skin was involved in 11 (13.9%) cases. Vascular and neural involvement was seen in 16 (20.3%) and 6 (7.6%) patients respectively. Regional lymph nodes were involved in 32 (40.5%) of the patients. Far metastasis was seen only in 1 (1.3%) patient. Conclusion: Our study results showed that approximately 80% of patients were in grade II or III at the beginning of the diagnosis. These results are similar to other studies in Iran: In a study in Emam Khomeini hospital, nearly 80% of the patients were at grade II or III of their disease. The percentage of patients in grade III was higher in our study (7). Although this study was performed on patients with breast cancer in a 3 years period, the number of the samples studied was higher than this study. One of the other advantages of this study was that in this study the pathology slides of the patients instead of their pathology reports were reviewed. This may reduce the possibility of the mistakes. Since our study was record based, some patients were excluded from the study due to incomplete records. Also, the diagnosis of disease was based on the pathology report at the time of the patient's referral. This may limit the generalizability of our study results. In our study, regional lymph node involvement was seen in 40.5% of the patients. Jamali et al. found that the possibility of lymph node involvement will increase in higher stages of the disease and all patients in grade III of the disease had axillary lymph node involvement (7).

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In our study, nipple and skin involvement was seen in 13.9% of the patients. Also, vascular involvement was seen in 20.3% of the patients. This is indicative of late referral of the patients. This problem may have different causes. Previous studies in Iran showed that one of the most important causes of the late referral of the patients is lack of enough knowledge (8). Although some concerns remain about the role of Breast Self-Examination (BSE) in decreasing the mortality of women related to breast cancer (9, 10), their knowledge about the breast mass that may be found accidentally is valuable. Referral of patients in the late stages of their disease which is associated with vascular, skin and nipple involvement and also regional lymph node involvement is indicative of lack of enough knowledge regarding the disease. Effective interventions should be considered to increase the women's knowledge about breast cancer. We recommend prospective studies using pathology slides to evaluate the grade of the disease. Acknowledgements: This paper is based on a medical student's thesis and we should thank the research committee of the faculty of medicine of Hormozgan University of Medical Sciences (HUMS) for their help and support. We also should thank all the members of the pathology ward in Shahid Mohammadi Hospital for their help and cooperation. References: 1. Azarm T, Harirchian M, Bahmanziari F, Raei H, Mehrabi S, Haghi S, Naghie et al. Cancer epidemiology in Isfahan province: Retrospective

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International Electronic Journal of Medicine (IEJM) October 2011; Volume 1, Issue 1, Pages: 3-6 study, 1990-95. Journal of Research In Medical Sciences 2000;2(5): 112109 2. R. Malekpour Afshar, MH. Larizadeh. Concordance Standards of Breast Cancer Pathology Reporting: with International A 4Year Study in Kerman. Journal of Rafsanjan University of Medical Sciences 2006;4-B(4): 286293 3. Mousavi SM, Montazeri A, Mohagheghi MA, Jarrahi AM, Harirchi I. Breast cancer in Iran: an epidemiological review. Breast J. 2007; 13(4): 383-391. 4. Farshbaf Khalili A., Shahnazi M., Ghahvechi A., Thorabi Sh.Performance conditions of breast cancer screening methods and its efficient factors among women referring to health centers of Tabriz.Iranian Journal of Nursing Research 2009;4(12-13): 27-38. 5. Mansourian HR, Nikookar L. Correlation between mammogram and sonogram findings with histopathologic examination in females over 30 years old with palpable breast mass. JOURNAL OF SHAHID SADOUGHI UNIVERSITY OF MEDICAL SCIENCES AND HEALTH SERVICES 2000;4(7): 15-8

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6. Sina A, Jalili A, Abdi B, Ghara Aghaji R. Study of the mammographic findings and correlation of breast tumors with the pathological results in Imam Khomeini Hospital, Urmia. URMIA MEDICAL JOURNAL 2002;3(13): 219-213 7. Jamali M, Irvanloo G, Farzan S. The study of relationship between aggresive ductal breast carcinoma and axillary lymph node involvement. THE JOURNAL OF TEHRAN FACULTY OF MEDICINE 2001;1(59): 28-26 8. Gholizade L, Shahvari Z, Mohamadhoseini S. Barriers Related to Clinical Breast Examination in Women Who Referred to Health and Medical Centers of Gachsaran. Dena, Quarterly Journal of Yasuj Faculty of Nursing And Midwifery 2008;3(1-2): 55-63 9. Mahboobi HR, Khorgoei T, Eftekhar F. New Recommendations about Breast Self Examination. Iran J Cancer Prev. 2010; Vol3, No4, p.155-6. 10. Muttappallymyalil J, Sreedharan J, Venkatramana M, Thomas M. Attitude and Practice of Nurses in Imparting Knowledge on Breast Self Examination to Women in Ajman, United Arab Emirates. Iran J Cancer Prev. 2010; Vol3, No3, p.139-44.

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Scientific Letter

Evaluation of the Microsoft office familiarity of the medical students of Hormozgan Medical University in 2006 Ebrahim Khaje 1, Keramat Allah Jahanshahi Hamidreza Mahboobi 5, 6 123456-

2, 3

, Nasim Arabzade 1, Nima Nesari 1, Zahra Jahangiri

3, 4

,

Infections & Tropical Disease Research Center, Hormozgan University of Medical Sciences (HUMS), Iran Behavioural and Neurosciences Research Center, Hormozgan University of Medical Sciences(HUMS), Iran Student Committee, Education Development Center (EDC), Hormozgan University of Medical Sciences(HUMS), Iran Hormozgan Fertility & Infertility Research Center, Hormozgan University of Medical Sciences(HUMS), Iran Hormozgan Cardiovascular Disease Research Center, Hormozgan University of Medical Sciences(HUMS), Iran Payame Noor University (PNU), Iran

Please cite this paper as: Khaje E, Jahanshahi KA, Arabzade N, Nesari N, Jahangiri Z, Mahboobi HR. Evaluation of the Microsoft office familiarity of the medical students of Hormozgan Medical University in 2006. Int Elec J Med 2011; 1(1): 9-10 Corresponding author: Keramat Allah Jahanshahi, Student Committee, Education Development Center (EDC), Hormozgan University of Medical Sciences (HUMS), Iran, Tel: +98.9364300250. The ability to access, evaluate and use information in each profession is one of the most effective materials of individual success. Accessing updated medical information is vital for physicians (1-5). In a descriptive cross sectional study performed in Bandar Abbas, the capital city of Hormozgan province in the southern part of Iran. Data the internet and computer usage was examined among medical students. All of the medical students were included in our study. Students who didn’t agree to participate in our study were excluded. Data was collected using a questionnaire that contained demographic information and 21 questions regarding internet and computer usage. The usage of internet, word, powerpoint, excel, outlook and access was assessed by multiple choice question (always, often, sometimes, never). Each answer received 0 to 3 points and for each student the summed score was assumed. The data was entered in SPSS 13 software and the descriptive statistics were used for data analysis. Out of 118 students, 88 (74.5%) were female. Among all of them, 83% had personal computer (PC) and 80.5% used internet sometimes or never. Their internet usage was less than an hour in each day in 43.2% of the students and 18.6% of them never used internet. The most visited websites were entertainment (49%), Email (45.8%) and medical websites (44.8%).

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Int Elec J Med 2011; 1(1):7-8

International Electronic Journal of Medicine (IEJM) October 2011; Volume 1, Issue 1, Pages: 7-8 Among all the students, 41.9% were using internet in their home and university and 40.2% were using internet only in useful. About 36.8% of the students evaluated it as slightly useful and 43.6% of them reported that the equipment of internet centers of the university were well. About 68.3% reported that these equipments aren’t enough in the dormitory. Students frequently reported shortages in the number of the computers in the centers (62.7%). Most of the shortage of the ‫ ﺍﻣﮑﺎﻧﺎﺕ‬of the university was the speed of the internet (42.5%) and the number of the educational classes (40.7%). There was no statistically significant relationship between age and sex and the internet usage among medical students. However students who had a personal computer (PC) used the internet more frequently (P