Mar 31, 2017 - We examined the global incidence and mortality rates of liver cancer, and evaluated the association between incidence/mortality and ...
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OPEN
International incidence and mortality trends of liver cancer: a global profile
received: 07 November 2016
Martin C. S. Wong1,2, Johnny Y. Jiang3, William B Goggins1, Miaoyin Liang1, Yuan Fang1, Franklin D. H. Fung1, Colette Leung1, Harry H. X. Wang4,5, Grace L. H. Wong2,6,7, Vincent W.S. Wong2,6,7 & Henry L. Y. Chan2,6,7
accepted: 03 March 2017 Published: 31 March 2017
We examined the global incidence and mortality rates of liver cancer, and evaluated the association between incidence/mortality and socioeconomic development (Human Development Index [HDI] and Gross Domestic Product [GDP]) using linear regression analysis. The average annual percent change (AAPC) of the trends was evaluated from join-point regression analysis. The global incidence of liver cancer varied widely by nine-fold, and was negatively correlated with HDI (men: r = −0.232, p = 0.003; women: r = −0.369, p
