International Journal of Current Medical and Pharmaceutical Research
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International Journal of Current Medical and Pharmaceutical Research Available Online at http://www.journalcmpr.com
RESEARCH ARTICLE ROLE OF TESTOSTERONE IN MODIFICATION OF ISCHEMIC HEART DISEASE Tanveer A Khan1*., Awais A Zaidi1., Lubna Shakir1., Mahtab A Khan2,3., Arsalan Ali1., Ayesha Hussain1.,Muhammad Yousaf1., Haroon Babar4 and Muhammad Ans5 1Faculty of Pharmacy, Hajvery University, Lahore-Pakistan 2Institute of Experimental and Clinical Pharmacology and Toxicology, University of Lübeck, Germany 3Bahauddin Zakariya University, Multan-Pakistan 4Chaudhary Pervaiz Elahi Institute of Cardiology (C.P.E.I.C), Multan-Pakistan 5Riphah International University Lahore-Pakistan ARTICLE INFO
ABSTRACT
Article History:
The objective of this study was to assess the testosterone role in modification of ischemic heart disease. All subjects were male aged between 30 to 80 years. At the start of study, blood pressure, serum testosterone, lipid profile and left ventricular function were recorded. Males who were at high risk of cardiovascular disease have low endogenous testosterone level. The testosterone therapy, 250mg/2mlweekly (Intramuscularly) for six months was sufficient to lower the risk of further cardiac complications by decreasing serum total cholesterol, low density lipoprotein and triglycerides levels (p
