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This tissue section is from a carcinosarcoma of the right fallopian tube of a 69-year-old woman. The tumor, measuring 12.4 Ã 8.5 Ã. 4 cm, consisted of a ...
International Journal of Surgical Pathology http://ijs.sagepub.com/
A Doggy Face in an Ugly Neoplasm Chrisoula D. Scopa and Helen P. Kourea INT J SURG PATHOL 2006 14: 226 DOI: 10.1177/1066896906290821 The online version of this article can be found at: http://ijs.sagepub.com/content/14/3/226
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A Doggy Face in an Ugly Neoplasm Chrisoula D. Scopa, MD, and Helen P. Kourea, MD
T
his tissue section is from a carcinosarcoma of the right fallopian tube of a 69-year-old woman. The tumor, measuring 12.4 × 8.5 × 4 cm, consisted of a high-grade adenocarcinoma admixed with mesenchymal elements that exhibited myogenic differentiation. Numerous atypical mitoses were noted, one of which popped out as a doggy face wearing a Santa Claus-like cap. It has been speculated that specific centrosomal alterations, which lead to a limited variety of atypical mitotic figures might not be a random result but a distinct event that is possibly involved in carcinogenesis.1
Reference Figure 1.
1. Batistatou A. Mitoses and cancer. Med Hypotheses. 2004;63:281-282.
From the Department of Pathology, University of Patras Medical School, Patras, Greece. Address correspondence to: Chrisoula D. Scopa, MD, PO Box 1174, 261 10 Patras, Greece; e-mail: cdscopa@ med.upatras.gr.
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