Intra-erythrocyte Magnesium Is Associated with Gamma-Glutamyl ...

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Jan 11, 2011 - with Gamma-Glutamyl Transferase in Obese Children ... furthermore, serum GGT was associated with IEM, independently of body mass index.
Biol Trace Elem Res (2011) 143:835–843 DOI 10.1007/s12011-010-8949-x

Intra-erythrocyte Magnesium Is Associated with Gamma-Glutamyl Transferase in Obese Children and Adolescents Maryam Tohidi & Asghar Ghasemi & Farzad Hadaegh & Shamsi Arbabi & Firoozeh Hosseini Isfahani

Received: 17 October 2010 / Accepted: 28 December 2010 / Published online: 11 January 2011 # Springer Science+Business Media, LLC 2011

Abstract This study aims at determining the association between markers of hepatic injury and serum, urinary, and intra-erythrocyte magnesium concentrations and dietary magnesium intake in obese children and adolescents. In a case–control study, 42 obese children and adolescents (8–18 years) and 42 sex- and puberty-matched controls were studied. Serum, urinary, and intra-erythrocyte magnesium levels, indices of insulin sensitivity, and liver enzymes were measured. Dietary magnesium intake was assessed using a food frequency questionnaire. Obese children and adolescents exhibited insulin resistance as determined by a higher fasting insulin and the HOMA-IR (p