detected). Figure 2: Dia/Dib HRM melt profile. The Diego HRM genotyping method produced melt curves characteristic of the three genotypes, DIA/DIA, DIB/DIB ...
Palmitoleic acid inhibits RANKL-induced osteoclastogenesis and bone resorption by suppressing NF-κB and MAPK signalling pathways. Van Heerden, B. (1); ...
hepatitis C virus co-infection. It relies on age, aspartate- and ... Patients with ICD-10 E11 (T2DM) diagnostic code whose lab assessments were completed ...
The Lokomat (Hocoma Inc., www.hocoma. com) was used as DGO for locomotion training. Linear drives on hip and knee joints provided torques to the subject ...
than 1indicates the risk factor is beneficial. Table 1. Regression analysis. The combined 10 year experience with corpus callosotomy at two children's hospitals.
1 Dept of Medicine, University of Thessaly, Larisa; 2 Dept of Obstetrics & Gynecology, Koutlimbaneio & Triantafylleio Hospital, Larisa; 3 Hygiene Lab, Dept of ...
No. of UK service personnel were evacuated to R4 for non-combat trauma in the year following cessation of combat operations? How do civilian and military ...
THE OPERATION OF CHOICE FOR VAGINAL VAULT SUSPENSION IN THE POST-MESH AGE;. A simpler and less complicated procedure than Sacral ...
Mark Hayes, Peter Watt & Alan Richardson. Environmental Extremes Laboratory, Eastbourne, UK. Fire Service Instructors' Working Practices: A United Kingdom ...
Treatment A New Oral Direct Thrombin Inhibitor, Dabigatran Etexilate, Compared With Enoxaparin for. Prevention of Thromboembolic Events Following Total ...
Despite the lack of strong medical evidence percutaneous mitral valve repair (PMVR) using the MitraClip®-system is increasingly performed in patients.
Cecectomy. Right hemicolectomy*. Left hemicolectomy*. Transverse colectomy. Sigmoidectomy. Multiple segment colectomy*. Partial colectomy*. Laparoscopic ...
of cancers of known stage that are diagnosed early (I/II) or late (III/IV). ... as published by the National Cancer Intelligence Network. â 2012 data is from CAS1406 ...
It is an indigenous pioneer plant that invades poorly managed grasslands and cultivated ... (bankrupt bush, slangbos or vaalbos). Grassroots: Newsletter of the.
Annual Skills Mastery Assessment (ASMA) Exam was developed. ... the mastery of terminal ability outcome statements as ... Gregory L. Alston, Bryan L. Love.
Auditing the use of Continuous Cardiac. Monitoring at Mater Dei Hospital. Abela M, Asciak R, Camilleri M, Bonanno N, Theuma F, Cassar A. Bilocca D, Zammit C ...
The technique for adductor canal block ... Ulrik Grevstad, Effect of Adductor canal block versus femoral nerve block on Quadriceps strength, mobilization, and ...
The facilitator programme aims to support cancer prevention, reduce the barriers to cancer screening and increase early diagnosis. In NHS Greater Glasgow.
Czech Republic; 7 â Department of Neurology, Charles University in Prague, Faculty of ... Five randomized clinical trials (MR CLEAN, ESCAPE, SWIFT PRIME, ...
in Three Sympatric Guenons in the Taï National Park, Côte d'Ivoire ... Erin E. Kane2, M. Alexandra Wilkins2, Frederic M. Gnepa3, David J.Daegling1, W. Scott ...
complex with biochemical relapse in prostate cancer patients. ... 1 Princess Margaret Cancer Centre, University Health Network 2 National Cancer Centre ...
atomoxetine, buspirone, bupropion, dextroamphetamine and mixed amphetamine salts. The efficacy meta-analysis was obtained to methylphenidate versus ...
by other leukocytes, mainly eosinophils. With the new MACSxpress Technology, untouched human neutrophils can be isolated from anticoagulated whole blood ...
ASA, SOFA, body mass index, preoperative albumin and lymphocyte count ... SOFA score showed a significant correlation with occurrence of pneumonia (p ...
Tertiary hyperparathyroidism is a frequent, serious problem in patients with advanced chronic kidney disease (CKD). This is a state of excessive secretion of ...
Outcomes of sub-total vs. total parathyroidectomy in renal hyperparathyroidism Antony Sorial (Academic FY2), Yaseen Motala (FY2), Nishant Cherian (FY2), Helen Doran (Consultant General & Endocrine Surgeon). Department of General Surgery – Salford Royal Hospital NHS Foundation Trust
Introduction
Methods
Tertiary hyperparathyroidism is a frequent, serious problem in patients with advanced chronic kidney disease (CKD). This is a state of excessive secretion of parathyroid hormone after longstanding secondary hyperparathyroidism resulting in hypercalcaemia. It manifests clinically with malaise, bone pain, metabolic complications and calcium deposition.
A retrospective review of all parathyroidectomies for renal hyperparathyroidism in a tertiary referral centre between 2000 and 2014. Groups were sub-divided into total (T) and sub-total (ST) parathyroidectomy. MM was graded as: • 1 (Vit-D/Calcium) • 2 (Cinacalcet) • 3 (Cinacalcet + Vit-D/Calcium).
Overall, there is approximately a 10% risk of recurrence or persistent disease in those requiring parathyroidectomy. This may be due to a hyper-functioning or missed neck gland, or, if transplanted, hyperplasia of the autograft1.
Hypercalcaemia
Hypocalcaemia
0
3.2
3.2) 2.2-2.8 ) (3.01-3.2)
Severity grade of hypercalcaemia
Severity of hypocalcaemia post-op
Results
16 14
22 T and 10 ST cases were identified. 1 ST case was excluded from long-term follow-up as the patient died 20 days post-op due to a cardiac arrhythmia. This was not attributed to surgery and the patient’s calcium levels postop were within the normal range.
No. of patients
Medical management (MM) can be used to control disease progression in secondary hyperparathyroidism. However, surgery may be indicated In patients who do not respond to appropriate MM, or where there is severe hyperparathyroidism with hypercalcaemia1. Total (T) and sub-total (ST) parathyroidectomy are the most common procedures performed. Much of the literature reports higher rates of disease recurrence with ST compared to T2. However, ST may be associated with fewer post-operative complications and reduced in-hospital stay.
Severity grading
12
ST
10
T
8 6
*
4 2 0
Figure 1. Parathyroid adenoma
ST (n = 10) Mean age
Aim To compare the outcomes of sub-total and total parathyroidectomy in patients with renal hyperparathyroidism.
