Low intracellular zinc induces oxidative DNA damage, disrupts p53 ...

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Dec 24, 2002 - Thus, low intracellular zinc status causes oxidative DNA damage ..... Crow, J. P., Sampson, J. B., Zhuang, Y., Thompson, J. A. & Beckman, J. S..
Low intracellular zinc induces oxidative DNA damage, disrupts p53, NF␬B, and AP1 DNA binding, and affects DNA repair in a rat glioma cell line Emily Ho and Bruce N. Ames* University of California, Berkeley, CA 94720; and Children’s Hospital Oakland Research Institute, Oakland, CA 94609 Contributed by Bruce N. Ames, November 7, 2002

Approximately 10% of the U.S. population ingests