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MAGNESIUM HYDROXIDE FOR PROTECTION ... - Semantic Scholar
isoenzymes. Clinica Chimica Acta 1973;45:235-42. 19 Moss DW, Whitby LG. A simplified heat inactivation method for investigating alkaline phosphatase.
21 Research report
Fluoride 44(1)21–26 January-March 2011
Magnesium hydroxide for protection against fluoride toxicity in rabbits Khandare, Kumar, Rao
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MAGNESIUM HYDROXIDE FOR PROTECTION AGAINST FLUORIDE TOXICITY IN RABBITS Arjun Khandare,a Uday Kumar,b Shanker Raoc Hyderabad, India.
SUMMARY: The present study was undertaken to assess the potential of magnesium hydroxide, (Mg(OH)2, to alleviate fluoride (F) toxicity in rabbits. Eighteen 2.5-monthold New Zealand white rabbits of both sexes were divided equally into three groups: 1 (control), 2 (F group), and 3 (F + Mg group). F was administered orally (10 mg F ion/ kg bw/day) to the group 2 animals while group 3 received 20 mg Mg(OH)2/kg bw/day plus the foregoing amount of F. After 7 months, 24-hr urine, blood, and fecal samples were collected for three consecutive days. As expected, serum F and total alkaline phosphatase (ALP) in group 2 became significantly higher (p
