Mammalian electrophysiology on a microfluidic ... - Semantic Scholar
Recommend Documents
Oct 6, 2015 - main objective of the study was to determine whether cryoablation ... PV ostia was carried out with the Arctic Front Cryo Ablation Catheter.
Sep 15, 2005 - (c) Vozzi, G.; Flaim, C.; Ahluwalia, A.; Bhatia, S. Biomaterials. 2003, 24, 2533-2540. (3) Chang, S. C. N.; Rowley, J. A.; Tobias, G.; Genes, N. G.; ...
Mar 4, 2016 - Here we present an experimental platform, coral-on-a-chip, combining micro- ... carbon per year3, exceeding 10% of marine calcium carbonate.
percentage of differences in these residues between the pig. DRBC allele and the human DRBI-OlO allele was significantly lower (29%) than that between the ...
Jul 8, 2016 - Abstract: The human enteroendocrine L cell line NCI-H716, expressing taste receptors and taste signaling elements, constitutes a unique ...
M. Hee-Jong, P. Gun-Woo, L. Sang-Bum, A. Kyungwon, and L. Jai-Hyung, ... be obtained by etching a cane used in the manufacture of microstructured fibres.
Nov 10, 2015 - inconvincible that sperm can successfully find the egg just by randomly swimming, without any guidance. Chemotaxis has been proposed to be ...
Aug 2, 2017 - Shahrukh Khan@, Shravan Kumar#, Shivani Banchariya!, and Raj Kumar#,*. @School of Biotechnology, Gautam Buddha University, Greater ...
May 26, 2016 - retinal degeneration. By conducting extracellular recording, we examined the electrophysiological properties of V1 in S334ter-line-3 rats (a ...
Mar 1, 2016 - This phenomenon is known as membrane fouling1. For the .... in the filter cake, when it consists of soft colloids. When, using ..... or other third party material in this article are included in the article's Creative Commons license,.
oped to explain how internal implicit processes are ..... result of the trial, whether the participant won or lost the bet according to if his or her bet matches the random number generator's .... test was used to test for within-group differences fo
reentrant tachycardia induction with antegrade conduction through 1 ..... cardia with dissociated VA conduction, was present in 3 patientsâ2 with RAI and 1 with ...
Nov 30, 2010 - Funding: This project was funded by the Leverhulme Trust (Grant number A20080076) awarded to AMTL. The funders had no role in study ...
It is unclear how primitive life forms originated from ... artificial mammalian cell would open a plethora of new ... basic steps to create artificial cells and present an ...
recently emphasized by the discovery of supernumerary abnormal .... from kidney RNA sample were cloned and sequenced to confirm the specificity of the PCR ...
Catheter-directed intervention to treat atrial fibrillation (AF) is becoming widely accepted procedure in current clinical practice. For assessment of pulmonary vein ...
A. Y. Lau, L. P. Lee, and J. W. Chan, âAn integrated optofluidic platform for ... and ionization that forms a low-density free-electron plasma within the lipid bilayer ...
Dec 28, 2010 - Prokineticin 2, a cysteine-rich secreted protein, is another strong candidate (PK2; Cheng et al., 2002). In the SCN,. PK2 mRNA is rhythmically ...
Although Gonda and Radding (13) could not observe in vitro RecA-promoted pairing of molecules sharing only 30 bp of homologous sequence, recent in vivo.
Nov 18, 2013 - and sarcoplasmic reticulum Ca2+-release events, causing delayed after-depolarizations/triggered activity in pAF. ConclusionsâIncreased ...
May 11, 2011 - Quan Guo,1 Sarah M. McFaul,1 and Hongshen Ma1,2,3,*. 1Department of Mechanical Engineering, University of British Columbia, 2054-6250 ...
Modular microfluidic valve structures based on reversible thermoresponsive ionogel actuators. Fernando Benito-Lopez,*a,c Marta Antoñana-DÃez,a,b Vincenzo ...
John Oakey,c David W. M. Marr,b Philippe Bado,d Mark A. Dugand and Ali A. Said d ..... 9 S. Fiedler, S. G. Shirley, T. Schnelle and G. Furgh, Anal. Chem.,. 1998 ...
May 14, 2015 - manuscripts will then undergo technical and English editing, typesetting, proof correction and be presented for the ... Principal Investigator-Heart, Lung, Blood and Vascular Medicine Institute. University of ..... Miami Lakes, FL).
Mammalian electrophysiology on a microfluidic ... - Semantic Scholar
Jun 28, 2005 - a glass pipette against the membrane of a cell. Carefully applied ... a 12-mm glass coverslip, permitting placement on the stage of an inverted ...
Mammalian electrophysiology on a microfluidic platform Cristian Ionescu-Zanetti*†, Robin M. Shaw†‡§, Jeonggi Seo*, Yuh-Nung Jan‡, Lily Y. Jan‡¶, and Luke P. Lee*储 *Department of Bioengineering, University of California, Berkeley, CA 94720; ‡Howard Hughes Medical Institute and Department of Physiology and Biochemistry, University of California, San Francisco, CA 93143-0725; and §Division of Cardiology, Department of Medicine, University of California, San Francisco, CA 93143-0124 Contributed by Lily Y. Jan, April 25, 2005
The recent development of automated patch clamp technology has increased the throughput of electrophysiology but at the expense of visual access to the cells being studied. To improve visualization and the control of cell position, we have developed a simple alternative patch clamp technique based on microfluidic junctions between a main chamber and lateral recording capillaries, all fabricated by micromolding of polydimethylsiloxane (PDMS). PDMS substrates eliminate the need for vibration isolation and allow direct cell visualization and manipulation using standard microscopy. Microfluidic integration allows recording capillaries to be arrayed 20 m apart, for a total chamber volume of
