Substance Abuse
ISSN: 0889-7077 (Print) 1547-0164 (Online) Journal homepage: http://www.tandfonline.com/loi/wsub20
Marijuana use and mortality following orthopedic surgical procedures Andrew S. Moon, Walter Smith, Sawyer Mullen, Brent A. Ponce, Gerald McGwin, Ashish Shah & Sameer M. Naranje To cite this article: Andrew S. Moon, Walter Smith, Sawyer Mullen, Brent A. Ponce, Gerald McGwin, Ashish Shah & Sameer M. Naranje (2018): Marijuana use and mortality following orthopedic surgical procedures, Substance Abuse, DOI: 10.1080/08897077.2018.1449054 To link to this article: https://doi.org/10.1080/08897077.2018.1449054
Accepted author version posted online: 20 Mar 2018.
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Publisher: Taylor & Francis Journal: Substance Abuse DOI: https://doi.org/10.1080/08897077.2018.1449054
ORIGINAL RESEARCH Marijuana use and mortality following orthopedic surgical procedures
Andrew S. Moon, BS1,2ORCID icon, Walter Smith, BS2, Sawyer Mullen, BS2, Brent A. Ponce, MD2, Gerald McGwin, PhD3,4, Ashish Shah, MD2, Sameer M. Naranje, MD, MRCS2
1
Tufts University School of Medicine, Boston, Massachusetts, USA
2
Department of Orthopaedics, University of Alabama at Birmingham, UAB Highlands,
Birmingham, Alabama USA 3
Department of Epidemiology, School of Public Health, University of Alabama at Birmingham,
Birmingham, Alabama USA 4Department of Ophthalmology, University of Alabama at Birmingham, Birmingham, Alabama, USAAre Dr. McGwin’s departments Epidemiology and Orthopaedics as in the MS. or Epidemiology and Ophthalmology?
Corresponding Author Sameer Naranje, MD, MRCS
2 University of Alabama at Birmingham 1313 13th Street South, Suite 226A Birmingham, AL 35205 Email:
[email protected]
Abstract Background: The association between marijuana use and surgical procedures is a matter of increasing societal relevance that has not been well studied in the literature. The primary aim of this study is to evaluate the relationship between marijuana use and in-hospital mortality, as well as to assess associated comorbidities in patients undergoing commonly billed orthopedic surgeries. Methods: The National Inpatient Sample (NIS) database from 2010 to 2014 was used to determine the odds ratios for the associations between marijuana use and in-hospital mortality, heart failure (HF), stroke, and cardiac disease (CD) in patients undergoing five common orthopedic procedures: hip (THA), knee (TKA), and shoulder arthroplasty (TSA), spinal fusion, and traumatic femur fracture fixation. Results: Of 9,561,963 patients who underwent one of the five selected procedures in the fouryear period, 26,416 (0.28%) were identified with a diagnosis of marijuana use disorder. In hip and knee arthroplasty patients, marijuana use was associated with decreased odds of mortality compared to no marijuana use (p
