Fondecyt national grants (£200.000 each) and co-investigator in 9 Fondecyt proposals. She is a Re- viewing Editor for Current Vascular Pharmacology and ...
Meet Our Editorial Board Member
Current Vascular Pharmacology, 2018, Vol. 16, No. 5 1
Meet Our Editorial Board Member Dr. Paola Casanello Pontificia Universidad Catolica de Chile Santiago Chile
Paola graduated as a Midwife in 1996 (Universidad de Concepción, Chile), specialized in Perinatology (1998) and trained in NICU. In 2003 obtained her MSc and later (2007) her PhD both in Biological Sciences/Physiology. Presently, she is an Associate Professor at the Division of Obstetrics and Gynecology, and the Division of Pediatrics, Department of Neonatology, in the School of Medicine at
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PUC (since 2014), and the leader of the Programming and Perinatal Epigenetics Lab. She has published over 56 full papers, has lead 3 associative national grants (Fondef, 2 Anillo, £450.000 each), 4
Paola Casanello
Fondecyt national grants (£200.000 each) and co-investigator in 9 Fondecyt proposals. She is a Reviewing Editor for Current Vascular Pharmacology and Editor in Ars Medica (PUC, Chile). SELECTED PUBLICATIONS [1]
Muñoz-Muñoz E, Krause BJ, Uauy R., Casanello P. LGA-newborn from patients with pregestational obesity present reduced adiponectin-mediated vascular relaxation and endothelial dysfunction in fetoplacental arteries. J Cell Physiol 2018 (in press).
[2]
Caniuguir A, Krause BJ, Hernandez C, Uauy R, Casanello P. Markers of early endothelial dysfunction in intrauterine growth restriction-derived human umbilical vein endothelial cells revealed by 2D-DIGE and mass spectrometry analyses. Placenta 2016; 41: 14-26.
[3]
Krause BJ, Hernandez C, Caniuguir A, Vasquez-Devaud P, Carrasco-Wong I, Uauy R, Casanello P. Arginase-2 is cooperatively up-regulated by nitric oxide and histone deacetylase inhibition in human umbilical artery endothelial cells. Biochem Pharmacol 2016; 99: 53-9.
[4]
Krause BJ, Carrasco-Wong I, Casanello P, et al. Micro-RNAs Let7e and 126 in plasma as markers of metabolic dysfunction in 10 to 12 years old children. PLoS One. 2015; 10: e0128140.
[5]
Casanello P, Schneider D, Herrera EA, Uauy R, Krause BJ. Endothelial heterogeneity in the umbilico-placental unit: DNA methylation as an innuendo
[6]
Krause BJ, Costello PM, Muñoz-Urrutia E, Lillycrop KA, Hanson MA, Casanello P. Role of DNA methyltransferase 1 on the altered eNOS expres-
[7]
Krause BJ, Hanson MA, Casanello P. Role of Nitric Oxide in Placental Vascular Development and Function. Placenta 2011; 32: 797-805.
of epigenetic diversity. Front Pharmacol 2014; 5: 49.
sion in human umbilical endothelium from intrauterine growth restricted fetuses. Epigenetics 2013; 8(9): 944-52.
[8]
Krause B, Sobrevia L, Casanello P. Epigenetics: New concepts of old phenomena in vascular physiology. Curr Vasc Pharmacol 2009; 7: 513-20.
[9]
Casanello P, Escudero C, Sobrevia L. Equilibrative Nucleoside (ENTs) and Cationic Amino Acid (CATs) transporters: Implications in foetal endothelial dysfunction in human pregnancy diseases. Curr Vasc Pharmacol 2007; 5: 65-89.
[10]
Casanello P, Sobrevia L. Intrauterine growth retardation is associated with reduced activity and expression of the cationic amino acid transport systems y+/hCAT-1 and y+/hCAT-2B, and lower activity of nitric oxide synthase in human umbilical vein endothelial cells. Circ Res 2002; 91: 127-34.
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