implemented variants of a candidate reference measure- ... in place but not the tools by which to comply. In this respect, two initiatives .... criterion to judge adequate performance of a network member. ..... graphic, and MS resolution). The latter
ObjectiveâTo determine whether measurement of baseline serum concentrations of total thyroxine (T4), triiodothyro- nine (T3), free T4, and thyrotropin ...
concentrations within the reference range (Jensen et al. 1996; Peterson et al. 1997;. Ramsey et al. 1997; Scott-Moncrieff et al. 1998; Dixon and Mooney 1999;.
garded as an important in-vitro diagnostic test for assessing thyroid function. ..... requested via email from [email protected]. 12.2 Interpretation. 1.
Dec 20, 2016 - Background/Aims: Although a low triiodothyronine (T3) state is closely associated with heart failure (HF), it is uncertain whether total T3 levels ...
metrologic optimus software.pdf. metrologic optimus software.pdf. Open. Extract. Open with. Sign In. Main menu. Displayi
Both total T,* and total T, are decreased in protein+nergy malnutrition ... binding prealbumin, thyroid-binding albumin and albumin in plasma, and it is the free ...
Ramsden and Farmer (8) and Nishinaga et al. (9). .... ine was applied to samples of frozen serum pools. Sam- ples were prepared and analyzed in three different ...
binding site by site-directed mutagenesis. ... other serpins, this glycosylation site is highly con- ..... Y, Seo H, Matsui N, Refetoff S 1991 Molecular cloning.
Thyroxine (T4) caused increases in protein degradation, that were blocked by leupeptin, a proteinase inhibitor previously shown to inhibit Ca2+-dependent ...
Apr 7, 1973 - abnormal and whose thyroid function tests show conflicting results. .... Acute thyroiditis (de Quervain's thyroiditis), by causing a damaged ...
Tagung: 'GPS 99 Geometrische Produktspezifikation und âpruefung, 1999, (in German). [3] H. Soons, Accuracy of Multi-Axis Machines, PhD-thesis, Eindhoven ...
chitect i2000 system (Abbott Diagnostics, Santa Clara, CA, USA). The TFT results obtained ... Sungkyunkwan University School of Medicine, 81 Irwon-ro, Gangnam-gu, ... Despite its high prevalence, significant interference caused by THAA is ...
safety and quality as well as to cold supply chain optimization. Furthermore, these systems are ... (d) time intervals at journey transit sites e.tc. (Costa et al. 2013).
Oct 30, 2003 - traceability in different phases of the system development are ... system development life cycle based on these requirements [Ram01].
range 0.35â5.5mU/l) were measured using chemi- luminescence immunoassay on a Siemens ADVIA. Centaur analyser (Frimley, UK). Method reproducibility,.
Requirements Traceability Matrix. Call Center Enhancements to I.D.A.. In
Delivered. Solution? In Custom Interface? In Customization per. GAP analysis?
used as a reference material for lithium isotopic composition (Flesch et al., 1973). ...... e changed VFC resistor for a brand new one from Ohmite in MAT252. 4030 ...
Bargarh district of western Orissaduring 1996 to 1999along ... Bargarh district of Orissa,which was.already identified .... Gonda (UP),sixin Delhi and one in Kerala.
to be a cause of an atherogenic fasting lipid profile by increasing low density lipoprotein cholesterol (LDL-C) and decreasing high density lipoprotein cholesterol.
thyroxine (fT4), 3,5,3'-triiodothyronine (T3), and provocative tests of thyroid secretory reserve (e.g., thyroid stimulating hormone [TSH] response test) have been ...
boleh diberikan dalam dos yang lebih rendah untuk mencegah kesan- Maklumat
kesan sampingan daripada berlaku. jika anda ada kencing manis, anda.
request from Monobind Inc. 12.1 Assay Performance. 1. It is important that the
time of reaction in each well is held constant to achieve reproducible results. 2.
Jun 3, 2009 - treated M. nigra, while silkworm larvae fed on thyroxine treated M. multicaulis produced longer unbreakable filament. Key words: Bombyx mori, ...
trials using common samples, i.e., 5 lyophilized and 33 frozen native ... Providing support to the European legislation, EN/ISO. Standard ... surement of thyroxine (T4), the free rather than the total ... 15194 guidelines will be given elsewhere.
Clinical Chemistry 51:1 161–168 (2005)
Endocrinology and Metabolism
Metrologic Traceability of Total Thyroxine Measurements in Human Serum: Efforts to Establish a Network of Reference Measurement Laboratories Linda M. Thienpont,1* Katleen Van Uytfanghe,1 John Marriot,2 Peter Stokes,2 Lothar Siekmann,3 Anja Kessler,3 David Bunk,4 and Susan Tai4
Background: Assuring/demonstrating metrologic traceability of in vitro diagnostics necessitates the availability of measurand-specific reference measurement systems (RMSs) and the possibility for industry to work with competent reference measurement laboratories (RMLs). Here we report the results of a European project to investigate the feasibility of developing a RMS for serum total thyroxine. Methods: Four candidate RMLs (cRMLs) developed/ implemented variants of a candidate reference measurement procedure (cRMP) based on isotope dilution– liquid chromatography–mass spectrometry. The sole constraint implemented was calibration with a common thyroxine primary calibrator. The RMPs were externally validated and assessed for comparability in round-robin trials using common samples, i.e., 5 lyophilized and 33 frozen native sera. At the same time, the performance of the cRMLs organized in a network was assessed. For uniform external quality assessment, common performance specifications were agreed on. Results: All cRMLs performed the cRMPs with fulfillment of the predefined specifications: total and between-laboratory CVs
