atively large dose of a-salc~xone was used in hopes of blocking the cffects of endogenoais opiate substarnces. (endorphins). hfethods. Six healthy volunteers (5 ...
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Naloxone and nlorphine inhibit gastric emptying of solids
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Receivctf September 2 l , 198 I C H , \ ~ ~ I - X >MN. , C., S. N . S{.ILLIVAN, M . CII~~MREHlogy, 868: 279 - 284. KENT. 1959. The effects of ~laoa-phimeand other drtags on N a % ~ oW, . S . , R . C. HEADING. .I. WII.SON,and L. F. n~otility of the terminal ileum. Gastroenterology, 36: 5 10-523. I ~ U - X W T1979. T . Reversal of narcotic inda~ccddelay in EDIN. R., J . LI;NDBER(;,L. TERENII;~, A. I~AFIL.STROM,gastric emptying and parc~cetananlalssorption by naloxonc. Br. Meci. J . 2: 11841. 'I'. H o K F E ~ '.I~I. , KEWENTER, and H. AHLMAN. 1980. Evidence for vagal enkephalinergic neural control of the feline N L ~ I MW O ,. S.. R. C'. MEADIN(;, J . WILSON, P. 'T'oT~I~I.!..aa~cl 1,. F. PRI~SCOTT. 1075. Inhibition of gastric cr81pXying- and pylorus and stomach. Gastroenterology. 78: 492 -497. FELDMAN, M . , J . H. WA(.SII, alld 1. L. '~'AYLOK.1980. Effect drug rabstsrpticm by narcotic analgesics. H r . .I. ('lin. of nalnxone and ~norphineon gastric acid secreticrn arid on PB~arrnaccul. 2: 509 5 1 3. PER'T,C. B . , and S. H . SNY~IER. 8973. Opiatc rcccptor serum gastrin and pancreatic polypeptide concentrations in humans. Gastroenterology. 79: 294-298. dernorrstration in r ~ e r v c ~tissue. s Science (Washingtc'rn, KONT~JREK, S . .!., J. TASLEK, N . CIESZKOWSKI, J . JAWOREK, D.C.), 179: 1011 - 1014. POLAK,9 . M., S. N. SBJL,L,IP'AN. S. K. 131,oohf. ['. I;,!('~iaARWISII. 198 1 . Effect of I B I O ~ ~ ~ I ~ I W I~ I LLO X ~~P [ I LP B ~ o~n MAGI~EJ. D. F. 1975. Action of rnorphia~esulphate on stinamstilnulatcd gastric and pancreatic sccl.ction. hrai. J . lared gastric secretion in dogs. Gastroenterology, 68: Gastroent. 76: 44 -46. 1340- 1343. MCKAY,5 . S.. B. I>.I-INAKER, and L. A. Tu~ru~~.ric;i. ICBW1 .
