Nanotoxicology - The University of Iowa College of Public Health

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PMCID: in process. Baltrusaitis J, Cwiertny DM, Grassian VH. Adsorption of sulfur dioxide on hematite and goethite particle surfaces. Phys Chem Chem Phys.
NANOTOXICOLOGY PUBLICATIONS 2007-PRESENT Abbas AO, Donovan MD, Salem AK. Formulating poly(lactide-co-glycolide) particles for plasmid DNA delivery. J Pharm Sci. 2008 Jul;97(7):2448-61. Review. PMID: 17918737. PMCID: N/A. Abdulrab A, Algobaty F, Salem AK, Mohammed YA. Acute bacterial meningitis in adults: a hospital based study in Yemen. Jpn J Infect Dis. 2010 Mar;63(2):128-31. PMID: 20332577. PMCID: N/A. Aldave AJ, Bourla N, Yellore VS, Rayner SA, Khan MA, Salem AK, Sonmez B. Keratoconus is not associated with mutations in COL8A1 and COL8A2. Cornea. 2007 Sep;26(8):963-5. PMID: 17721297. PMCID: N/A. Aldave AJ, Sonmez B, Bourla N, Schultz G, Papp JC, Salem AK, Rayner SA, Yellore VS. Autosomal dominant cornea plana is not associated with pathogenic mutations in DCN, DSPG3, FOXC1, KERA, LUM, or PITX2. Ophthalmic Genet. 2007 Jun;28(2):57-67. PMID: 17558846. PMCID: N/A. Aldave AJ, Yellore VS, Bourla N, Momi RS, Khan MA, Salem AK, Rayner SA, Glasgow BJ, Kurtz I. Autosomal recessive CHED associated with novel compound heterozygous mutations in SLC4A11. Cornea. 2007 Aug;26(7):896-900. PMID: 17667634. PMCID: N/A. Aldave AJ, Yellore VS, Sonmez B, Bourla N, Salem AK, Khan MA, Rayner SA, Glasgow BJ. A novel variant of combined granular-lattice corneal dystrophy associated with the Met619Lys mutation in the TGFBI gene. Arch Ophthalmol. 2008 Mar;126(3):371-7. PMID: 18332318; PMCID: PMC2860538. Aldave AJ, Yellore VS, Yu F, Bourla N, Sonmez B, Salem AK, Rayner SA, Sampat KM, Krafchak CM, Richards JE. Posterior polymorphous corneal dystrophy is associated with TCF8 gene mutations and abdominal hernia. Am J Med Genet A. 2007 Nov 1;143A(21):2549-56. PMID: 17935237. PMCID: N/A. Arthur JC, Lich JD, Ye Z, Allen IC, Gris D, Wilson JE, Schneider M, Roney KE, O'Connor BP, Moore CB, Morrison A, Sutterwala FS, Bertin J, Koller BH, Liu Z, Ting JP. Cutting edge: NLRP12 controls dendritic and myeloid cell migration to affect contact hypersensitivity. J Immunol. 2010 Oct 15;185(8):4515-9. Epub 2010 Sep 22. PMID: 20861349. PMCID: in process. Baltrusaitis J, Cwiertny DM, Grassian VH. Adsorption of sulfur dioxide on hematite and goethite particle surfaces. Phys Chem Chem Phys. 2007 Nov 7;9(41):5542-54. Epub 2007 Aug 30. PMID: 17957310. PMCID: N/A. Baltrusaitis J, Grassian VH. Carbonic acid formation from reaction of carbon dioxide and water coordinated to Al(OH)3: a quantum chemical study. J Phys Chem A. 2010 Feb 18;114(6):23506. PMID: 20104872. PMCID: N/A. Baltrusaitis J, Jayaweera PM, Grassian VH. XPS study of nitrogen dioxide adsorption on metal oxide particle surfaces under different environmental conditions. Phys Chem Chem Phys. 2009 Oct 1;11(37):8295-305. Epub 2009 Jul 2. PMID: 19756286. PMCID: N/A.

Baltrusaitis J, Schuttlefield J, Jensen JH, Grassian VH. FTIR spectroscopy combined with quantum chemical calculations to investigate adsorbed nitrate on aluminium oxide surfaces in the presence and absence of co-adsorbed water. Phys Chem Chem Phys. 2007 Sep 28;9(36):4970-80. Epub 2007 Jul 10. PMID: 17851593. PMCID: N/A. Baltrusaitis J, Usher CR, Grassian VH. Reactions of sulfur dioxide on calcium carbonate single crystal and particle surfaces at the adsorbed water carbonate interface. Phys Chem Chem Phys. 2007 Jun 21;9(23):3011-24. Epub 2007 Feb 28. PMID: 17551626. PMCID: N/A. Clapper JD, Pearce ME, Guymon CA, Salem AK. Biotinylated biodegradable nanotemplated hydrogel networks for cell interactive applications. Biomacromolecules. 2008 Apr;9(4):1188-94. Epub 2008 Feb 29. PMID: 18307307. PMCID: N/A. Cwiertny DM, Young MA, Grassian VH. Chemistry and photochemistry of mineral dust aerosol. Annu Rev Phys Chem. 2008;59:27-51. PMID: 18393675. PMCID: N/A. Elzey S, Grassian VH. Nanoparticle dissolution from the particle perspective: insights from particle sizing measurements. Langmuir. 2010 Aug 3;26(15):12505-8. PMID: 20590108. PMCID: N/A. Fenton MS, Marion KM, Salem AK, Hogen R, Naeim F, Hershman JM. Sunitinib inhibits MEK/ERK and SAPK/JNK pathways and increases sodium/iodide symporter expression in papillary thyroid cancer. Thyroid. 2010 Sep;20(9):965-74. PMID: 20629553. PMCID: N/A. Fiegel J, Garcia-Contreras L, Thomas M, VerBerkmoes J, Elbert K, Hickey A, Edwards D. Preparation and in vivo evaluation of a dry powder for inhalation of capreomycin. Pharm Res. 2008 Apr;25(4):805-11. Epub 2007 Jul 27. PMID: 17657592. PMCID: N/A. Garcia-Contreras L, Fiegel J, Telko MJ, Elbert K, Hawi A, Thomas M, VerBerkmoes J, Germishuizen WA, Fourie PB, Hickey AJ, Edwards D. Inhaled large porous particles of capreomycin for treatment of tuberculosis in a guinea pig model. Antimicrob Agents Chemother. 2007 Aug;51(8):2830-6. PMCID: PMC1932523. Goforth R, Salem AK, Zhu X, Miles S, Zhang XQ, Lee JH, Sandler AD. Immune stimulatory antigen loaded particles combined with depletion of regulatory T-cells induce potent tumor specific immunity in a mouse model of melanoma. Cancer Immunol Immunother. 2009 Apr;58(4):517-30. Epub 2008 Aug 22. PMID: 18719913. PMCID: in process. Grassian VH, Meyer G, Abruña H, Coates GW, Achenie LE, Allison T, Brunschwig B, Ferry J, Garcia-Garibay M, Gardea-Torresdey J, Grey CP, Hutchison J, Li CJ, Liotta C, Ragauskas A, Minteer S, Mueller K, Roberts J, Sadik O, Schmehl R, Schneider W, Selloni A, Stair P, Stewart J, Thorn D, Tyson J, Voelker B, White JM, Wood-Black F. Chemistry for a sustainable future. Environ Sci Technol. 2007 Jul 15;41(14):4840-6. PMID: 17711191. PMCID: N/A. Grassian VH, O’Shaughnessy PT, Adamcakova-Dodd A, Pettibone JM, Thorne PS. Inhalation exposure study of titanium dioxide nanoparticles with a primary particle size of 2 to 5 nm. Environ Health Perspect. 2007 Mar;115(3):397-402. PMCID: PMC1849915. Hatch CD, Grassian VH. 10th Anniversary review: applications of analytical techniques in laboratory studies of the chemical and climatic impacts of mineral dust aerosol in the Earth's

atmosphere. J Environ Monit. 2008 Aug;10(8):919-34. Epub 2008 Jul 11. Review. PMID: 18688461. PMCID: N/A. Hong L, Krishnamachari Y, Seabold D, Joshi VB, Schneider G, Salem AK. Intracelluar release of 17-β estradiol from cationic polyamidoamine dendrimer surface modified poly lacticco-glycolic acid microparticles improves osteogenic differentiation of human mesenchymal stromal cells. Tissue Eng Part C Methods. 2010 Sep 30. [Epub ahead of print] PMID: 20883116. PMCID: PMC3045071. Intra J, Glasgow JM, Mai HQ, Salem AK. Pulsatile release of biomolecules from polydimethylsiloxane (PDMS) chips with hydrolytically degradable seals. J Control Release. 2008 May 8;127(3):280-7. Epub 2008 Feb 11. PMID: 18342975. PMCID: N/A. Intra J, Salem AK. Characterization of the transgene expression generated by branched and linear polyethylenimine-plasmid DNA nanoparticles in vitro and after intraperitoneal injection in vivo. J Control Release. 2008 Sep 10;130(2):129-38. PMCID: PMC2603176. Intra J, Salem AK. Fabrication, characterization and in vitro evaluation of poly(D,L-lactide-coglycolide) microparticles loaded with polyamidoamine-plasmid DNA dendriplexes for applications in nonviral gene delivery. J Pharm Sci. 2010 Jan;99(1):368-84. PMCID: PMC2882054. Intra J, Salem AK. Rational design, fabrication, characterization and in vitro testing of biodegradable microparticles that generate targeted and sustained transgene expression in HepG2 liver cells. J Drug Target. 2010 Aug 3. [Epub ahead of print] PMID: 20681752. PMCID: as supplied by publisher Krishnamachari Y, Geary SM, Lemke CD, Salem AK. Nanoparticle Delivery Systems in Cancer Vaccines. Pharm Res. 2010 Aug 19. [Epub ahead of print] PMID: 20721603. PMCID: in process. Krishnamachari Y, Salem AK. Innovative strategies for co-delivering antigens and CpG oligonucleotides. Adv Drug Deliv Rev. 2009 Mar 28;61(3):205-17. Epub 2009 Jan 19. Review. PMCID: PMC2656598. Liu Y, Gibson ER, Cain JP, Wang H, Grassian VH, Laskin A. Kinetics of heterogeneous reaction of CaCO3 particles with gaseous HNO3 over a wide range of humidity. J Phys Chem A. 2008 Feb 21;112(7):1561-71. Epub 2008 Jan 31. PMID: 18232670. PMCID: N/A. Mudunkotuwa IA, Grassian VH. Citric acid adsorption on TiO2 nanoparticles in aqueous suspensions at acidic and circumneutral pH: surface coverage, surface speciation, and its impact on nanoparticle-nanoparticle interactions. J Am Chem Soc. 2010 Oct 27;132(42):1498694. PMID: 20919713. PMCID: N/A. Navea JG, Xu S, Stanier CO, Young MA, Grassian VH. Effect of ozone and relative humidity on the heterogeneous uptake of octamethylcyclotetrasiloxane and decamethylcyclopentasiloxane on model mineral dust aerosol components. J Phys Chem A. 2009 Jun 25;113(25):7030-8. PMID: 19485395. PMCID: N/A. Pan Q, Mathison J, Fearns C, Kravchenko VV, Da Silva Correia J, Hoffman HM, Kobayashi KS, Bertin J, Grant EP, Coyle AJ, Sutterwala FS, Ogura Y, Flavell RA, Ulevitch RJ. MDP-induced

interleukin-1beta processing requires Nod2 and CIAS1/NALP3. J Leukoc Biol. 2007 Jul;82(1):177-83. Epub 2007 Apr 2. PMID: 17403772. PMCID: N/A. Park H, Grassian VH. Commercially manufactured engineered nanomaterials for environmental and health studies: important insights provided by independent characterization. Environ Toxicol Chem. 2010 Mar;29(3):715-21. PMID: 20821499. PMCID: N/A. Pearce ME, Melanko JB, Salem AK. Multifunctional nanorods for biomedical applications. Pharm Res. 2007 Dec;24(12):2335-52. Epub 2007 Aug 8. Review. PMID: 17684708. PMCID: N/A. Peters TM, Elzey S, Johnson R, Park H, Grassian VH, Maher T, O'Shaughnessy P. Airborne monitoring to distinguish engineered nanomaterials from incidental particles for environmental health and safety. J Occup Environ Hyg. 2009 Feb;6(2):73-81. PMID: 19034793. PMCID: in process. Pettibone JM, Cwiertny DM, Scherer M, Grassian VH. Adsorption of organic acids on TiO2 nanoparticles: effects of pH, nanoparticle size, and nanoparticle aggregation. Langmuir. 2008 Jun 1;24(13):6659-67. Epub 2008 Jun 7. PMID: 18537279. PMCID: N/A. Petushkov A, Intra J, Graham JB, Larsen SC, Salem AK. Effect of crystal size and surface functionalization on the cytotoxicity of silicalite-1 nanoparticles. Chem Res Toxicol. 2009 Jul;22(7):1359-68. PMID: 19580308. PMCID: N/A. Prather KA, Hatch CD, Grassian VH. Analysis of atmospheric aerosols. Annu Rev Anal Chem (Palo Alto Calif). 2008;1:485-514. Review. PMID: 20636087. PMCID: N/A. Prince AP, Kleiber P, Grassian VH, Young MA. Heterogeneous interactions of calcite aerosol with sulfur dioxide and sulfur dioxide-nitric acid mixtures. Phys Chem Chem Phys. 2007 Jul 14;9(26):3432-9. Epub 2007 May 24. PMID: 17664967. PMCID: N/A. Prince AP, Kleiber PD, Grassian VH, Young MA. Reactive uptake of acetic acid on calcite and nitric acid reacted calcite aerosol in an environmental reaction chamber. Phys Chem Chem Phys. 2008 Jan 7;10(1):142-52. Epub 2007 Nov 21. PMID: 18075693. PMCID: N/A. Reig N, Jiang A, Couture R, Sutterwala FS, Ogura Y, Flavell RA, Mellman I, van der Goot FG. Maturation modulates caspase-1-independent responses of dendritic cells to Anthrax lethal toxin. Cell Microbiol. 2008 May;10(5):1190-207. PMCID: PMC2861895. Roca M, Zahardis J, Bone J, El-Maazawi M, Grassian VH. 310 nm irradiation of atmospherically relevant concentrated aqueous nitrate solutions: nitrite production and quantum yields. J Phys Chem A. 2008 Dec 25;112(51):13275-81. PMID: 19053540. PMCID: N/A. Rubasinghege G, Grassian VH. Photochemistry of adsorbed nitrate on aluminum oxide particle surfaces. J Phys Chem A. 2009 Jul 9;113(27):7818-25. PMID: 19534452. PMCID: N/A Rubasinghege G, Lentz RW, Park H, Scherer MM, Grassian VH. Nanorod dissolution quenched in the aggregated state. Langmuir. 2010 Feb 2;26(3):1524-7. PMID: 19950935. PMCID: N/A.

Rubasinghege G, Lentz RW, Scherer MM, Grassian VH. Simulated atmospheric processing of iron oxyhydroxide minerals at low pH: roles of particle size and acid anion in iron dissolution. Proc Natl Acad Sci U S A. 2010 Apr 13;107(15):6628-33. Epub 2010 Apr 1. PMID: 20360560; PMCID: 2872379. Salem AK, Fenton MS, Marion KM, Hershman JM. Effect of sunitinib on growth and function of FRTL-5 thyroid cells. Thyroid. 2008 Jun;18(6):631-5. PMID: 18578612. PMCID: N/A. Salem AK, Weiner GJ. CpG oligonucleotides as immunotherapeutic adjuvants: innovative applications and delivery strategies. Adv Drug Deliv Rev. 2009 Mar 28;61(3):193-4. PMCID: PMC2667912. Schuttlefield J, Al-Hosney H, Zachariah A, Grassian VH. Attenuated total reflection fourier transform infrared spectroscopy to investigate water uptake and phase transitions in atmospherically relevant particles. Appl Spectrosc. 2007 Mar;61(3):283-92. PMID: 17389068. PMCID: N/A. Schuttlefield J, Rubasinghege G, El-Maazawi M, Bone J, Grassian VH. Photochemistry of adsorbed nitrate. J Am Chem Soc. 2008 Sep 17;130(37):12210-1. Epub 2008 Aug 23. PMID: 18722429. PMCID: N/A Usher CR, Baltrusaitis J, Grassian VH. Spatially resolved product formation in the reaction of formic acid with calcium carbonate (1014): the role of step density and adsorbed water-assisted ion mobility. Langmuir. 2007 Jun 19;23(13):7039-45. Epub 2007 May 15. PMID: 17500573. PMCID: N/A. Watanabe W, Thomas M, Clarke R, Klibanov AM, Langer R, Katstra J, Fuller GG, Griel LC, Fiegel J, Edwards D. Why inhaling salt water changes what we exhale. J Colloid Interface Sci. 2007 Mar 1;307(1):71-8. Epub 2006 Nov 15. PMID: 17161415. PMCID: N/A. Zhang H, Schmidt M, Murry DJ, Donovan MD. Permeation and systemic absorption of R- and S-baclofen across the nasal mucosa. J Pharm Sci. 2011 Jan 31. doi: 10.1002/jps.22499. [Epub ahead of print] PMID: 21283988. PMCID: In process Zhang XQ, Dahle CE, Baman NK, Rich N, Weiner GJ, Salem AK. Potent antigen-specific immune responses stimulated by codelivery of CpG ODN and antigens in degradable microparticles. J Immunother. 2007 Jul-Aug;30(5):469-78. PMID: 17589287. PMCID: N/A. Zhang XQ, Dahle CE, Weiner GJ, Salem AK. A comparative study of the antigen-specific immune response induced by co-delivery of CpG ODN and antigen using fusion molecules or biodegradable microparticles. J Pharm Sci. 2007 Dec;96(12):3283-92. PMID: 17497736. PMCID: N/A. Zhang XQ, Intra J, Salem AK. Comparative study of poly (lactic-co-glycolic acid)-poly ethyleneimine-plasmid DNA microparticles prepared using double emulsion methods. J Microencapsul. 2008 Feb;25(1):1-12. PMID: 18188727. PMCID: N/A. Zhang XQ, Intra J, Salem AK. Conjugation of polyamidoamine dendrimers on biodegradable microparticles for nonviral gene delivery. Bioconjug Chem. 2007 Nov-Dec;18(6):2068-76. Epub 2007 Sep 12. PMID: 17848077. PMCID: N/A.