New medicines to improve control and contribute to ... - Malaria Journal

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Oct 20, 2010 - Despite being one of the most prevalent tropical diseases, for many years malaria was not a commercial priority for the pharmaceutical industry.
Wells Malaria Journal 2010, 9(Suppl 2):I15 http://www.malariajournal.com/content/9/S2/I15

INVITED SPEAKER PRESENTATION

Open Access

New medicines to improve control and contribute to the eradication of malaria Timothy NC Wells From Parasite to Prevention: Advances in the understanding of malaria Edinburgh, UK. 20-22 October 2010

Despite being one of the most prevalent tropical diseases, for many years malaria was not a commercial priority for the pharmaceutical industry. However, in response to the emergence and spread of resistance to the available antimalarial drugs, there has been a renaissance in the discovery and development of new medicines to control the disease in the last few years. The persistent threat of resistance means that new molecules with novel mechanisms of action are continually required. Furthermore, the recent call for the elimination and eradication of malaria has prompted an extension of the stages of the life cycle of malaria parasites that should be targeted by new molecules. Recent advances in genome-based technologies and in vitro screening of whole parasites have broadened the range of therapeutic targets and are accelerating the development of a new generation of treatments for both malaria control and eradication. Published: 20 October 2010

doi:10.1186/1475-2875-9-S2-I15 Cite this article as: Wells: New medicines to improve control and contribute to the eradication of malaria. Malaria Journal 2010 9(Suppl 2):I15.

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© 2010 Wells; licensee BioMed Central Ltd. This is an open access article distributed under the terms of the Creative Commons Attribution License (http://creativecommons.org/licenses/by/2.0), which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.