New-onset atrial fibrillation in sepsis is associated with increased ...

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Jan 9, 2015 - February 2015 , Volume 23, Issue 2, pp 82–88 ... Gandhi, S., Litt, D. & Narula, N. Neth Heart J (2015) 23: 82. doi:10.1007/s12471-014-0641-x.
Neth Heart J (2015) 23:82–88 DOI 10.1007/s12471-014-0641-x

R e v i e w A rt i c l e

New-onset atrial fibrillation in sepsis is associated with increased morbidity and mortality Sumeet Gandhi · Dhanjit Litt · Neeraj Narula

Published online: 9 January 2015 © The Author(s) 2014. This article is published with open access at Springerlink.com

Abstract Background  The development of new-onset atrial fibrillation in sepsis has been associated with adverse outcomes. Methods  A systematic literature search was conducted to retrieve articles that investigated the association of new-onset atrial fibrillation in patients diagnosed with sepsis. The primary outcome of interest was the pooled risk ratio (RR) of in-hospital mortality in patients with new-onset atrial fibrillation and sepsis. Results  Six studies included 3100 patients with new-onset atrial fibrillation in sepsis and 36,900 patients without newonset atrial fibrillation in sepsis. The pooled RR for in-hospital mortality was 1.45 (95 % CI 1.32–1.60, p 

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