Nigerian children: response to calcium supplementation. J Trop Ped

Erratum Thacher, T., Glew, R. H., Isichei, C., Lawson, J. O., Scariano, J. K., Hollis, B. W. and VanderJagt, D. J. Rickets in Nigerian children: response to calcium supplementation. J Trop Ped 1999; 45: 202–207. It is regretted that the following three tables were omitted from the above paper. TABLE 1 Summary of the characteristics of subjects and controls Rachitic subjects (n ¼ 10)

Controls (n ¼ 10)

p value

Male/female Age (months) Weight (kg) Height (cm) MAC (cm) OFC (cm)

3/7 48:8 6 24:4* 13:7 6 4:8 88:9 6 14:3 15:5 6 1:9 50:1 6 2:4

6/4 47:8 6 26:6 12:4 6 3:2 91:5 6 13:9 14:8 6 0:8 48:4 6 1:9

NS NS NS NS NS

Serum albumin (g/l) Serum prealbumin (mg/l)

42 6 7 101 6 26

38 6 6 131 6 50

NS NS

*Mean 6 1 SD. MAC, mid-arm circumference; OFC, occipitofrontal circumference; NS, not statistically significant, p > 0:05.

TABLE 2 Summary of demographic data related to rickets Parameter

Rachitic subjects (n ¼ 10)

Controls (n ¼ 10)

6 23 6 10:3* 14 (5–36)‡ 14 (10–50)

1 NA 18 (14–22) 12 (10–18)

Family history of rickets Age of first symptoms of rickets (months) Age when breastfeeding stopped (months) Age when walking started (months) Median sunlight exposure (no. of subjects) 1–3 h/week 4–7 h/week 1–3 h/day 3 h/day Percentage of body not covered by clothing Median socioeconomic score

1 1 3 5

p value NS NS NS

1 1 2 6

30:4 6 7:3 3.4

23:7 6 6:6 3.6

NS NS

*Mean 6 1 SD; ‡ median (range); NA, not applicable; NS, not significant.

TABLE 3 Summary of biochemical parameters related to calcium homeostasis in rachitic subjects and controls Calcium

(mg/dl) Baseline 24 h 1 week 4 weeks 12 weeks Controls

Phosphorus

[ p]

(mg/dl)

8:7 6 0:7* [0.003]† 4 :5 6 1:3 9:4 6 1:0 [0.25] 4:7 6 1:8 10:3 6 1:2 [0.36] 5:2 6 1:9 9:3 6 0:4 [0.02] 4:3 6 0:8 9:5 6 0:6 [0.25] 4:5 6 0:9 9:8 6 0:5

5:6 6 0:9

Alkaline phosphatase

PTH

25-(OH)-D

1,25-(OH)2-D

[ p]

(U/l)

[ p]

(pg/ml)

[ p]

(ng/ml)

[ p]

(pg/ml)

[ p]

[0.05] [0.23] [0.71] [0.02] [0.04]

556 (383–1500)‡ 521 (380–1692) 649 (396–827) 487 (337–1357) 399 (274–1011)

[0.007] [0.005] [0.007] [0.005] [0.005]

5.3 (1–159) 5.9 (1–174) 2.1 (1–37) 36 (13–74) 55 (21–113)

[0.95] [0.16] [0.05] [0.07] [0.005]

9:6 6 4:5 10 6 4:1 10 6 3:8 11 6 4:2 11 6 4:9

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