Childs Nerv Syst DOI 10.1007/s00381-006-0086-7
ORIGINA L PA PER
Yong Ahn Byung-Kyu Cho Seung-Ki Kim You-Nam Chung Chang Sub Lee Il Han Kim Sei Won Yang Hee-Soo Kim Hyun Jib Kim Hee-Won Jung Kyu-Chang Wang
Optic pathway glioma: outcome and prognostic factors in a surgical series
Received: 30 June 2003 # Springer-Verlag 2006
H.-S. Kim Division of Pediatric Anesthesiology, Seoul National University Children’s Hospital, Seoul, South Korea Y. Ahn . B.-K. Cho . S.-K. Kim . Y.-N. Chung . C. S. Lee . K.-C. Wang Laboratory for Neuro-oncology at the Cancer Research Institute, Seoul National University Children’s Hospital, Seoul, South Korea
Y. Ahn . B.-K. Cho . S.-K. Kim . Y.-N. Chung . C. S. Lee . H. J. Kim . H.-W. Jung . K.-C. Wang Department of Neurosurgery, Seoul National University Children’s Hospital, Seoul, South Korea I. H. Kim Department of Radiation Oncology, Seoul National University Children’s Hospital, Seoul, South Korea S. W. Yang Department of Pediatrics, Seoul National University Children’s Hospital, Seoul, South Korea
K.-C. Wang (*) Division of Pediatric Neurosurgery, Seoul National University Children’s Hospital, 28 Yongon-dong, Chongno-gu, Seoul 110-744, South Korea e-mail:
[email protected] Tel.: +82-2-20723489 Fax: +82-2-7475130
Abstract Objects: The goals of this study were to evaluate the surgical outcomes of optic pathway glioma (OPG) and to analyze the prognostic factors related to the progression-free survival. Materials and methods: A
Introduction Optic pathway gliomas (OPGs) mainly occur during the first decade of life (75%) and account for approximately 1– 5% of all intracranial tumors [17]. The wide variability in tumor growth rate shown by OPGs has prevented generalizations of tumor behavior. Historically, OPGs have been believed to be congenital, benign, and self-limiting ham-
retrospective review was conducted on 33 patients who underwent surgery for OPG; these included 15 male and 18 female patients with a mean age of 8.3 years. The mean duration of followup was 52 months. Results and conclusions: The preservation rate of ipsilateral vision was 25%, while that of contralateral vision was 83% (P
