Antiviral Therapy 14:401–411
Original article Evaluation of transmitted HIV drug resistance among recently-infected antenatal clinic attendees in four Central African countries Avelin F Aghokeng1, Laurence Vergne 2, Eitel Mpoudi-Ngole1, Madeleine Mbangue3, Noe Deoudje4, Etienne Mokondji5, Wilfrid S Nambei6, Marlyse M Peyou-Ndi7, Jean-Jacques L Moka7, Eric Delaporte 2 and Martine Peeters 2* Virology Laboratory CRESAR/IMPM/Institut de Recherche pour le Développement (IRD), Yaoundé, Cameroon UMR145, Institut de Recherche pour le Développement (IRD) and University of Montpellier 1, Montpellier, France 3 Hôpital La Quintinie, Douala, Cameroon 4 Programme National de lutte contre le Sida/IST, N’Djamena, Chad 5 Laboratoire National de la Santé Publique, Brazzaville, Republic of Congo 6 Laboratoire National de Biologie, Bangui, Central African Republic 7 Organisation de Coordination pour la lutte contre les Endémies en Afrique Centrale (OCEAC), Yaoundé, Cameroon 1 2
*Corresponding author: E-mail:
[email protected]
Background: The rapid expansion of antiretroviral treatment in resource-limited settings is raising concerns regarding the emergence and transmission of HIV drug resistance (HIVDR). We evaluated the extent of transmission of drug-resistant HIV strains in four Central African countries: the Republic of Congo, Central African Republic, Chad and Cameroon. Methods: The World Health Organization (WHO) HIVDR threshold survey was implemented in major treatment areas in each country. Pregnant women who were aged
