Passive- and active-cigarette smoking: Effects on the levels of antioxidant vitamins, immunoglobulin classes and acute phase reactants Arinola O. G1*, Akinosun O. M1 and Olaniyi J. A2 1
Department of Chemical Pathology and Immunology, College of Medicine, University of Ibadan, Oyo State, Nigeria. 2 Department of Haematology, College of Medicine, University of Ibadan, Nigeria. Accepted 11 April, 2011
The levels of plasma immunoglobulin classes (IgG, A and M) and acute phase proteins (α 2macroglobulin (A2MG), C-reactive protein (CRP)) were determined using single radial immunodiffusion method. Also, determined in the plasma of the subjects were antioxidant vitamins (vitamins C and E) using spectrophotometric method. The participants were 30 subjects who had never smoked and not exposed to cigarette smoke (non smokers), 30 who had smoked at least 15 cigarettes per day for at least five years (active smokers) and 30 who had been exposed to cigarette smoke at least 2 cigarette/day on ≥5 days/wk for at least 5 years (passive smokers). Plasma levels of IgG, IgM, CRP and A2MG were significantly raised (p
