11 Mar 2013 ... clinical presentation, potential roles of pharmacotherapy and basic ...
Pharmacotherapy: a pathophysiologic approach / Joseph T. DiPiro, et al.
Applied Pathophysiology PHRM 1430 2017 Credit Hours: 3 Class contact hours: 3 hours/week in 2nd Term: Mondays and Wednesdays 9:00 -10:30am Lecture Location: 2nd Floor Lecture Theatre Apotex Centre
Course Coordinator: Dr. Mike Namaka (Room 319 Apotex Ctr, 474-8380, e-mail: namakamp@ms.umanitoba.ca Subject material will be introduced by different faculty members who are specialists in the field. Their names, subject area, and phone numbers are listed below: Instructor Dr. M. Namaka Rick Thurmeier Dr. Lori Wazny Dr. H. Iacovides Dr. D. Turcotte
Phone number 474-8380 namakamp@ms.umanitoba.ca 237-2630 rickthurmeier@outlook.com 787-2703 lwazny@hsc.mb.ca 474-8407 Harris.Iacovides@umanitoba.ca 272-3170 Dana.Turcotte@umanitoba.ca
Purpose of the Course: To understand the pathophysiological processes that contributes to human disease for selected organ systems. Course content will prepare pharmacy students for subsequent courses related to diagnosis and management of disease associated with pathophysiologic dysfunction / alterations.
Learning Outcomes: By the end of the course, students should be able to demonstrate the following: Learning outcome Bloom’s Taxonomy Level of Learning Define medical terminology as it applies to human disease Ideas – Knowledge states Describe selected diagnostic procedures used to diagnose a Ideas – Comprehension disease Summarize the etiology of a selected disease state Ideas – Comprehension Use a diagram or picture to explain a pathophysiological Connections - Application disease process Relate patient signs and symptoms to a pathophysiological disease process Connections – Analysis Propose mechanisms of medications that would be beneficial in selected disease states.
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Extensions – Synthesis
Background and Prerequisites Required: The pathophysiology course is designed such that students will have completed the necessary physiology lectures prior to coming to the pathophysiology class. If students have not yet covered a topic in their Human Physiology class, please ask them to review the information in the textbook entitled: “Human physiology: from cells to systems / Lauralee Sherwood, Robert Kell. 1st Canadian Edition. 2010. NJM Health Sciences Library RESERVE QT 104 S554ha 2010” or via the EBook entitled: Ganong’s Review of Medical Physiology. Kim E. Barrett, Susan M. Barman, Scott Boitano, Heddwen Brooks. 23rd Edition Online: Access Pharmacy http://proxycheck.lib.umanitoba.ca/libraries/online/proxy.php?http://www.accesspharmacy.com/r esourceToc.aspx?resourceID=11 It will be assumed that students have read the appropriate material in their physiology and pathophysiology texts prior to coming to class.
Assessment and Grading: Summative Assessment Exam Mid-Term Examination Final Examination (non-cumulative)
% of Final Grade 40% 60 %
Date TBA TBA (Scheduled by the University during exam week)
Exam Format: Midterm and Final examinations will be 2 hours in duration. Both the midterm and final exam will be multiple choice and/or short answer questions. Short answer questions may include diagram labelling, drawing a diagram to explain a disease process, listing facts, explanation of a pathophysiologic mechanism or interpretation a patient case to identify signs and symptoms related to a disease state. All questions covered in the examinations will be based on all material discussed in class plus the assigned reading material. Students will be assigned a letter grade for the course based on the following table listed below: Letter % Achieved Grade Point Description Grade 90 – 100
A+
4.5
Exceptional
80 – 89
A
4.0
Excellent
75 – 79
B+
3.5
Very good
70 – 74
B
3.0
Good
65 – 69
C+
2.5
Satisfactory
60 – 64
C
2.0
Adequate
50 – 59
D
1.0
Marginal
0 – 49
F
0
Failure
Assessment Policy: Students who cannot complete any aspects of the course for medical reasons must contact the course coordinator (Dr. Michael Namaka) at the earliest possible time. Please consult the 2
University of Manitoba’s Undergraduate Calendar and the Faculty of Pharmacy Student Handbook for specific regulations regarding academic dishonesty, attendance, examinations and scholastic progress. All students are expected to attend classes unless previously excused by the course coordinator. Class attendance is a mandatory requirement of the course. Academic Difficulties It is strongly recommended that if students are experiencing difficulty understanding the various topics covered throughout the course that they request help and feedback with the appropriate instructor by scheduling a mutually agreeable appointment. The contact information for all expert facilitators can be found on the first page of this syllabus. Student Accessibility Services (SAS) provides support and advocacy for students with disabilities and can provide students with academic accommodations. Students have to register with SAS to be eligible for academic accommodations. For more information, the SAS website can be accessed here: http://umanitoba.ca/student/saa/accessibility/index.html.
Course Textbooks and Reference Material: PATHOPHYSIOLOGY TEXTS Note: Access to e-books online requires authentication with library ID & password. Required Reading Texts: E-Books The majority of pre-class readings will be drawn from the following two textbooks: (Available from the Pharmacy Toolkit: http://libguides.lib.umanitoba.ca/pharmacy ) 1. Pathophysiology of disease: an introduction to clinical medicine / edited by Stephen J. McPhee, Gary D. Hammer. 6th Edition. Online: Access Pharmacy http://proxycheck.lib.umanitoba.ca/libraries/online/proxy.php?http://www.accesspharmac y.com/resourceToc.aspx?resourceID=17 2. Pharmacotherapy: a pathophysiologic approach / Joseph T. DiPiro, et al. 8th Edition. Online: AccessPharmacy http://proxycheck.lib.umanitoba.ca/libraries/online/proxy.php?http://www.accesspharmac y.com/resourceToc.aspx?resourceID=669 Recommended Texts: Robbins and Cotran pathologic basis of disease / V. Kumar, et al. Professional ed. Online: MD Consult http://proxycheck.lib.umanitoba.ca/libraries/online/proxy.php?http://home.mdconsult.com/das/bo ok/view/1249 Note: Print Textbooks on 2-hour reserve at the Neil John Maclean Health Sciences Library 1. Pathophysiology : the biologic basis for disease in adults and children / [edited by] Kathryn L. McCance, Sue E. Huether. 6th ed. 2010. NJM Health Sciences Library RESERVE QZ 4 P3027p6 2010 3
2. Essentials of pathophysiology : concepts of altered health states / Carol Mattson Porth. 3rd ed. Philadelphia: Lippincott Williams & Wilkins, 2011. NJM Health Sciences Library RESERVE QZ 4 P851e3 2011 3. Understanding pathophysiology / Sue E. Huether, Kathryn L. McCance. 4th ed. St. Louis, Mo: Mosby, 2008. NJM Health Sciences Library RESERVE QZ 4 H8903u4 2008 Suggested References for Physiology background (if required): 1. Ganong’s Review of Medical Physiology. Kim E. Barrett, Susan M. Barman, Scott Boitano, Heddwen Brooks. 23rd Edition Online: AccessPharmacy http://proxycheck.lib.umanitoba.ca/libraries/online/proxy.php?http://www.accesspharmacy.com/r esourceToc.aspx?resourceID=11 2. Human physiology: from cells to systems / Lauralee Sherwood, Robert Kell. 1st Canadian ed. 2010. NJM Health Sciences Library RESERVE QT 104 S554ha 2010
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PHRM 1430: Applied Pathophysiology Schedule Lecture Location: 2nd Floor Lecture Theatre: Mondays & Wednesdays 9:00 - 10:30 AM TOPIC
Date
STUDY TOPICS
Jan 4
No Classes PDW Atherosclerosis and stable angina
Jan 9 Cardiovascular Disease
FACILITATOR
Jan 11
Acute Coronary Syndromes
Jan 16
Hypertension
Jan 18
Heart Failure
Dr. D. Turcotte
Dr. Namaka
Diabetes
Jan 23 & 25
Diabetes Type I and Type II
Gastrointestinal Disorders
Jan 30 & Feb 1
Ulcers/GERD
Feb 6 & 8
Depression/Sleep Disorders/ADHD
R. Thurmier
Schizophrenia & Bipolar
R. Thurmier
Dr. Namaka
Mental Illness
Dr. Namaka
Mental Illness
Feb 13
Neurology
Feb 15
Neuropathic Pain
Midterm Winter Break
Feb 20 - 24
No Classes
Midterm Exam Outside of Class TBA
Feb ??
All above topics prior to Feb 15th topics
Room TBA
Arthritis
Feb 27 & Mar 1
Rheumatoid Arthritis/ Osteoarthritis
Dr. Namaka
Nephrology
Mar 6 & 8
Chronic Kidney Disease I /Chronic Kidney Disease II
Dr. L. Wazny
Dermatology/ Oncology
Mar 13 & 15
Psoriasis/Epilepsy
Dr. Namaka
Respiratory Disorders
Mar 20
Asthma
Respiratory Disorders
Mar 22
COPD
Hepatic disease
Mar 27
Acute Hepatitis
Dr. H. Iacovides
Hepatic disease Neurology Disorders Neurology Disorders Final Exam (Covering Material from Feb 27 to Apr 5) – Non Cumulative from Midterm
Mar 29 Apr 3 Apr 5 Scheduled after last day of classes Apr 7
Cirrhosis Multiple Sclerosis Parkinson’s Disease
Dr. H. Iacovides Dr, Namaka Dr. Namaka
Time and Location TBA
Dr. Namaka
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Dr. Namaka Dr. Namaka
