This Accepted Manuscript has not been copyedited and formatted. The final version may differ from this version.
Research Article: New Research | Sensory and Motor Systems
Presynaptic GABA receptors mediate temporal contrast enhancement in Drosophila olfactory sensory neurons and modulate odor-driven behavioral kinetics Temporal contrast enhancement in the Drosophila antennal lobe Davide Raccuglia1, Li Yan McCurdy1,2, Mahmut Demir3, Srinivas Gorur-Shandilya2, Michael Kunst1, Thierry Emonet3,4 and Michael N. Nitabach1,5,6 1
Department of Cellular and Molecular Physiology, Yale University School of Medicine, New Haven, CT 06520, USA 2
Interdepartmental Neuroscience Program, Yale University, New Haven, CT 06520, USA
3
Department of Molecular, Cellular and Developmental Biology, Yale University, New Haven, CT 06520, USA
4
Department of Physics, Yale University, New Haven, CT 06520, USA
5
Department of Genetics, Yale University School of Medicine, New Haven, CT 06520, USA
6
Program in Cellular Neuroscience, Neurodegeneration and Repair, Yale University School of Medicine, New Haven, CT 06520, USA DOI: 10.1523/ENEURO.0080-16.2016 Received: 13 April 2016 Revised: 4 July 2016 Accepted: 21 July 2016 Published: 25 July 2016
Author contributions: D.R., L.Y.M., M.D., S.G.-S., M.K., T.E., and M.N.N. designed research; D.R., L.Y.M., and M.D. performed research; D.R., L.Y.M., M.D., and S.G.-S. analyzed data; D.R. and M.N.N. wrote the paper; S.G.-S., M.K., and T.E. contributed unpublished reagents/analytic tools. Conflict of Interest: Authors report no conflict of interest. Work in the laboratory of M.N.N. was supported in part by the National Institute of Neurological Disorders and Stroke, National Institutes of Health (NIH) (R01NS055035, R01NS056443, R01NS091070), National Institute of General Medical Sciences, NIH (R01GM098931), and the Kavli Institute for Neuroscience. L.Y.M was supported by a Gruber Science Fellowship and NIGMS, NIH (T32GM007223). Correspondence should be addressed to: Michael N. Nitabach. E-mail:
[email protected] Cite as: eNeuro 2016; 10.1523/ENEURO.0080-16.2016 Alerts: Sign up at eneuro.org/alerts to receive customized email alerts when the fully formatted version of this article is published.
Accepted manuscripts are peer-reviewed but have not been through the copyediting, formatting, or proofreading process. This is an open-access article distributed under the terms of the Creative Commons Attribution 4.0 International (http://creativecommons.org/licenses/by/4.0), which permits unrestricted use, distribution and reproduction in any medium provided that the original work is properly attributed. Copyright © 2016 Society for Neuroscience
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