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Quantitative evaluation of microdistortions in Bowman's layer and corneal deformation after small incision lenticule extraction Running head: High resolution optical imaging of Bowman's layer
Rushad Shroff, MD,2 Mathew Francis, MTech,3 Natasha Pahuja, MD,2 Leio Veeboy, MTech,3 Rohit Shetty, MD, PhD, FRCS,1,2 Abhijit Sinha Roy, PhD.4
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Vice-Chairman, 2Cornea and Refractive Surgery Division, Narayana Nethralaya Foundation, Bangalore, India; 3Imaging, Biomechanics and Mathematical Modeling Solutions, Narayana Nethralaya Foundation, Bangalore, India; 4Chief Scientist, Imaging, Biomechanics and Mathematical Modeling Solutions, Narayana Nethralaya Foundation, Bangalore, India.
Corresponding Author: Dr. Abhijit Sinha Roy, PhD, Narayana Nethralaya Foundation, #258A Hosur Road, Bommansandra, Bangalore, India-560099. Email:
[email protected]
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Abstract
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Purpose: To quantitatively evaluate microdistortions in Bowman's layer and change in corneal
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stiffness after small incision lenticule extraction (SMILE).
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Methods: This was a prospective, longitudinal and interventional study. 30 eyes of 30 patients
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were screened preoperatively and underwent SMILE for treatment of myopia with astigmatism.
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Visual acuity, refraction, optical coherence tomography (OCT, Bioptigen Inc., USA) imaging of
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the layer and air-puff applanation (Corvis-ST, OCULUS Optikgerate Gmbh, Germany) was
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performed before and after surgery (1 day, 1 week and 1 month). The Bowman’s roughness
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index was defined as the enclosed area between the actual and an ideal smooth layer to quantify
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the microdistortions. A viscoelastic model was used to quantify the change in corneal stiffness
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using applanation.
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Results: Uncorrected distance visual acuity improved (p
