Rapidly progressive glomerulonephritis in a patient with advanced ...
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Pauci-immune' glomerulonephritis has been recognized as an important cause of rapidly progressive glomerulonephritis The paucity of immune deposits can be.
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Rapidly progressive glomerulonephritis in a patient with advanced ...
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Rapidly progressive glomerulonephritis in a patient with advanced renal cell carcinoma Martin Sommer, Ru¨diger Schmidt, Evelyne Lambrecht1, Heribert Fink2, Helmut Geiger and Tomas Lenz Medical Clinic IV, Division of Nephrology and 1Institute for Pathology, University Hospital, Johann Wolfgang Goethe University, Frankfurt am Main and 2Nephrologische Gemeinschaftspraxis, Darmstadt, Germany
Introduction Rapidly progressive glomerulonephritis (RPGN ) is a feature of many underlying diseases. We report on a patient who presented clinically with RPGN and in whom further diagnostic procedures revealed advanced renal cell carcinoma. This association is rare, and only a few cases with a grim renal prognosis have been reported in the literature [1,2].
Case A 41-year-old male patient was admitted to our hospital presenting with gross haematuria and oedema of the legs which had been present for 2 weeks. On admission, he had moderate to severe oedema of the legs; his temperature was 37°C, his pulse was regular at 88/min, his respiratory rate was 14/min and blood pressure was 220/120 mmHg. Physical examination was otherwise unremarkable except for a grade 2 systolic murmur along the left sternal border. The neurological examination was normal. Laboratory results revealed the following: plasma creatinine 2.1 mg/dl (normal
