Original Article
http://dx.doi.org/10.3349/ymj.2012.53.3.543 pISSN: 0513-5796, eISSN: 1976-2437
Yonsei Med J 53(3):543-549, 2012
Recent Changes in the Clinicopathologic Features of Korean Men with Prostate Cancer: A Comparison with Western Populations Seok-Soo Byun,1 Sangchul Lee,1 Sang Eun Lee,1 Eunsik Lee,2 Seong Il Seo,3 Hyun Moo Lee,3 Han Yong Choi,3 Cheryn Song,4 Hanjong Ahn,4 Young Deuk Choi,5 and Jin Seon Cho6 Department of Urology, Seoul National University College of Medicine, Seoul National University Bundang Hospital, Seongnam; 2 Department of Urology, Seoul National University College of Medicine, Seoul National University Hospital, Seoul; 3 Department of Urology, Sungkyunkwan University School of Medicine, Samsung Medical Center, Seoul; 4 Department of Urology, Asan Medical Center, University of Ulsan College of Medicine, Seoul; 5 Department of Urology, Yonsei University College of Medicine, Seoul; 6 Department of Urology, Hallym University School of Medicine, Chuncheon, Korea.
1
Received: March 21, 2011 Revised: July 8, 2011 Accepted: July 14, 2011 Corresponding author: Dr. Han Yong Choi, Department of Urology, Sungkyunkwan University School of Medicine, Samsung Medical Center, 50 Irwon-dong, Gangnam-gu, Seoul 135-710, Korea. Tel: 82-2-3410-3551, Fax: 82-2-3410-3027 E-mail:
[email protected] ∙ The authors have no financial conflicts of interest.
Purpose: The aim of this study was to evaluate the recent changes in the clinicopathologic features of prostate cancer in Korea and to compare these features with those of Western populations. Materials and Methods: We retrospectively reviewed the data of 1582 men undergoing radical prostatectomy for clinically localized prostate cancer between 1995 and 2007 at 10 institutions in Korea for comparison with Western studies. The patients were divided into two groups in order to evaluate the recent clinicopathological changes in prostate cancer: Group 1 had surgery between 1995 and 2003 (n=280) and Group 2 had surgery between 2004 and 2007 (n=1302). The mean follow-up period was 24 months. Results: Group 1 had a higher prostate-specific antigen level than Group 2 (10.0 ng/mL vs. 7.5 ng/mL, respectively; p
