2001). Thereafter, we computed weather variables at lag0â2/lag3â5 as described above for PM2.5. Self-reported education, medication use, health history, and ...
Research Ambient Fine Particulate Matter Exposure and Myocardial Ischemia in the Environmental Epidemiology of Arrhythmogenesis in the Women’s Health Initiative (EEAWHI) Study Zhu-ming Zhang,1 Eric A. Whitsel,2,3 P. Miguel Quibrera,2 Richard L. Smith,4 Duanping Liao,5 Garnet L. Anderson,6 and Ronald J. Prineas 1 1Epidemiologic
Cardiology Research Center, Department of Epidemiology and Prevention, Division of Public Health Sciences, Wake Forest University School of Medicine, Winston-Salem, North Carolina, USA; 2Departments of Epidemiology, 3Medicine, and 4Statistics and Operations Research, University of North Carolina at Chapel Hill, Chapel Hill, North Carolina, USA; 5Department of Health Evaluation Sciences, Pennsylvania State University, Hershey, Pennsylvania, USA; 6Fred Hutchinson Cancer Research Center, Seattle, Washington, USA
Background: Ambient particulate matter (PM) air pollution is associated with coronary heart disease, but the pathways underlying the association remain to be elucidated. Methods: We studied the association between PM and ischemia among 57,908 Women’s Health Initiative clinical trial participants from 1999–2003. We used the Minnesota Code criteria to identify ST-segment and T-wave abnormalities, and estimated T amplitude (microvolt) from resting, standard 12-lead electrocardiogram (ECG). We used U.S. Environmental Protection Agency’s monitor data to estimate concentrations of PM
