SC04.02 Management of Resistance to EGFR Tyrosine Kinase Inhibitors

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regulation of MED12 ((Mediator Complex Subunit 12) have been proposed as mechanisms of EMT. Then, How are we able to cope with these resistance?
S82

Ref.

Journal of Thoracic Oncology

Pts.

3

81

4 5 6 7 8

50 79 28 151 70

Mean age

T1: T2

72

41: 41

74.1 74.8 82 73.9 83

30: 42: 12: 91: 39:

21 37 17 60 31

Total dose (GyRBE)/ fractions 59.4-95.4/ 9-18 72/ 9 52.8-60/ 4 52.8-72/ 4-9 36-50/ 1 28-50/ 1

Vol. 12 No. 1S

F/U (months)

5-yr local control

5-yr causespeciļ¬c survival

5-yr overall survival

Toxicity grade 3