Zhu, Jian-Qin; Chen, Hui; Wang, Shao-Rong, Li, Yan; Fang, Wei-Shuo*.
Synthesis and hepatoprotective activity of glycoside conjugates of ursolic acid.
Chem J ...
Shaorong Wang Research Assiatant in Medicinal Chemistry Institute of Materia Medica Chinese Academy of Medical Sciences 2# Building, Jinri Kejiyuan, Jinyuan Road, Beijing 102600, China 86-13810695449 (Tel)
[email protected] [email protected]
Education 2004-2009 Ph. D. in Medicinal Chemistry, Peking Union Medical College Thesis Title: Design and systhesis of natrual product analogues and compound libraries based on pentacyclic triterpenoids and taxanes. Advisor: Professor Dali Yin, Professor Weishuo Fang 2000-2004 B. Sc. in Pharmacy, School of Pharmceutical Sciences, Peking University Thesis Title: Synthesis of anti-tumor glucose analogues containing phthalimide fragment. Advisor: Professor Zhongjun Li
Research experience September 2009-present Research Assistant, IMM/CAMS On the subject: Medicinal chemistry and chemical biology of bioactive natural products Publications Papers: 1. Zhu, Jian-Qin; Chen, Hui; Wang, Shao-Rong, Li, Yan; Fang, Wei-Shuo*. Synthesis and hepatoprotective activity of glycoside conjugates of ursolic acid. Chem J Chin Uni, in press. 2. Zhang, Shu-En; Tao, Jia-Yi; Zhao, Ying; Wang, Shao-Rong; Zhou, Di; Fang, Wei-Shuo*. Isolation, identification, semi-synthesis of aziditaxel derivatives and their biological evaluation. J Asia Nat Prod Res, 2012, 14, 463-475. 3. Wang, Shao-Rong; Fang, Wei-Shuo*. Design and synthesis of a dual linker for solid phase synthesis of oleanolic acid derivatives. Molecules, 2011, 16, 4748-4763. 4. Wang, Shao-Rong; Fang, Wei-Shuo*. Pentacyclic triterpenoids and their saponins with apoptosis-inducing activity. Curr Top Med Chem, 2009, 9, 1581-1596. 5. Fang, Wei-Shuo*; Wang, Shao-Rong. Structural studies of taxol analogues for drug discovery. Expert Opin Drug Dis, 2008, 3, 1109-1122. Conference Communications: 1. Shaorong Wang, Chungang Yang, Ana Angelica Alcaraz, James P. Snyder, Weishuo Fang.
Novel 4-Methyl-4-Deacetyl D-Seco Paclitaxel Analogues. 2012 National Medicinal Chemistry Symposium. Tucson, USA. 20-23 May, 2012. 2. Shaorong Wang, Chungang Yang, Weishuo Fang. Synthesis of Novel D-seco Paclitaxel Analogues. 2011 China Medicinal Chemistry Symposium. Guangzhou, China. 17-20 Nov, 2011. 3. Shaorong Wang, Weishuo Fang. Solid Phase Parellel Synthesis of Diverse Libraries of Oleanolic Acid with Antitumor Activity. 11th Tetrahedron Symposium. Beijing, China. 22-25 Jun, 2010. 4. Shaorong Wang, Weishuo Fang. Solid Phase Parellel Synthesis of Diverse Libraries of Oleanolic Acid. 2nd International Symposium on Combinatorial Sciences. Beijing, China. 19-23 Sept, 2009. Book Chapters: 1. Shao-rong Wang, Wei-shuo Fang. Structure modifications of taxol and the interactions of these analogues with microtubules. In: Institute of Materia Medica, Chinese Academy of Medical Sciences (ed.) Modern Studies of Traditional Chinese Medicine, Peking Union Medical College Press (Beijing), 2010, p.859-881.
