Sporadic conventional uterine leiomyoma. Tissue material. 2SC Somatic MED12 mutation. 1. FFPE. - c.130G>T, p.G44C. 2. FFPE. - c.131G>A, p.G44D. 3. FFPE.
Supplemental table 3. Results of 2SC immunohistochemical staining and MED12 exon 1/2 mutation status of 66 sporadic uterine leiomyomas.
Sporadic conventional uterine leiomyoma
Tissue material
1 2 3 4 5 6 7 8 9 10 11 12 13 14 15 16 17 18 19 20 21 22 23 24 25 26 27 28 29 30 31 32 33 34 35 36 37 38 39 40 41 42 43 44 45 46
FFPE FFPE FFPE FFPE FFPE FFPE FFPE FFPE FFPE FFPE FFPE FFPE FFPE FFPE FFPE FFPE FFPE FFPE FFPE FFPE FFPE FFPE FFPE FFPE FFPE FFPE FFPE FFPE FFPE FFPE FFPE FFPE FFPE FFPE FFPE FFPE FFPE FFPE FFPE FFPE FFPE FFPE FFPE FFPE FFPE FFPE
2SC -
Somatic MED12 mutation c.130G>T, p.G44C c.131G>A, p.G44D c.131G>A, p.G44D c.131G>A, p.G44D c.117-134del18, p.L39_G44delinsF wt IVS1-22_102del25 c.131G>A, p.G44D wt wt wt wt wt c.130G>T, p.G44C wt wt c.107T>G, p.L36R wt c. 122T>A, p.V41E wt wt wt c.131G>A, p.G44D IVS1-11_IVS1-2del10 c.131G>A, p.G44D c.146_166del21, p.P49_E55del wt c.131G>A, p.G44D c.130G>C, p.G44R wt wt wt c.141_155del15, p.Q48_S52del c.128A>C, p.Q43P wt c.131G>A, p.G44D wt c.107T>G, p.L36R wt wt c.131G>A, p.G44D wt c.130G>C, p.G44R c.100_117del18, p.D34_L39del c.131G>T, p.G44V c.130G>T, p.G44C
47 48 49 50 51 52 53 54 55 56 57 58 59 60 61 62 63 64 65 66
FFPE FFPE FFPE FFPE FFPE FFPE FFPE FFPE FFPE FFPE FFPE FFPE FFPE FFPE FFPE FFPE FFPE FFPE FFPE FFPE
-
NA wt c.118_144del27, p.N40_Q48del wt NA wt c.105_119del15, p.E35_N40delinsD c.107T>G, p.L36R wt c.131G>C, p.G44A c.131G>A, p.G44D c.130G>C, p.G44R c.130G>C, p.G44R wt c.121_138del18, p.V41_N46del c.131G>A, p.G44D c.131G>A, p.G44D wt wt wt
