Sudoku Puzzles for First-Year Organic Chemistry ...

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Glutamine. Gln Q. Glutamic Acid Glu E. Histidine. His. H. Isoleucine Ile. I. Threonine. Thr T. Tryptophan. Trp W. 1. 2. 3. 4. 5. 6. 7. 8. 9. P. T. E. His. Trp. Asn. Arg. Q.
P T

His Q

Trp

E Pro

His

Thr

Asn

Proline

E Proline

Glutamine

Asparagine

Glutamic Acid

R

N

Q

P

I

Glutamine

P

Tryptophan Isoleucine Arginine

N

Arg R Asn N Pro P Thr T Trp W

Arginine

Tryptophan

Threonine

Arg

1 Arginine 2 Asparagine 3 Proline 4 Threonine 5 Tryptophan

Isoleucine Asparagine Threonine

Arg

Gln

Asparagine

Gln

Trp E Q

Thr

Ile His

Gln Q 6 Glutamine 7 Glutamic Acid Glu E 8 Histidine His H 9 Isoleucine Ile I

-CH 2CO 2 H

-CH(Me)Et

Ser

Alanine

-H

Val

Leu

Serine

-CH 2OH

Gly

Ala

Leucine

Ser

Ile

Phenyl alanine

Asp

Val

-CH 2 SH

Aspartic Acid

Phenyl alanine

Alanine

-CH 2 Ph

Alanine

-CH(Me)Et

-CH 2 OH

-CH 2iPr

Val

Ile

Serine

-H

Leucine -CH(Me)Et

-CH 2CO 2H

1 2 3 4

Alanine Cysteine Phenyl alanine

A C F

Ala

Cys Phe

Cys -CH(Me) 2

Cysteine

-Me -CH 2 SH -CH 2 Ph

Leucine

L

Leu

-CH 2 iPr

5

Aspartic Acid

D

Asp

-CH 2 CO 2H

6

Glycine

G

Gly

7

Serine

S

Ser

8

Valine

V

Val

-CH(Me)2

9

Isoleucine

I

Ile

-CH(Me)Et

-H -CH 2 OH

Valine

-CH 2SH

-H

Cysteine

Cys

Aspartic Acid

Phe

Ser

Phenol Alcohol

O

RCONH 2

R

Acid

RNO2

Ester

O

O

RCH 2NH 2 RCH 2 OH

OH R

R

RCHO

O

OH R

O R

R

Amine

OH

Phenol

3

Acid

RCOOH

Ester

Alcohol

RCH 2 OH

4

Phenol

5

Ketone

6

Ester

RCOOR

Amide

RCONH 2

8

Nitro

RNO2

9

Amine

7

O R

RCH 2NH 2

O R

R

OH

OH OH

Ph-OH RCOR

H

O R

R

O R

O

R

OR

NH 2

O R

R

NH 2

O OH R

N

O

Aldehyde

Alcohol

N

O

Amide RCHO

RNO2

OH

RCHO

H

RCOR

H

Aldehyde

O

Nitro

NH 2

O

1 2

R

Ester

H

Aldehyde Ketone

OH

R

NH 2

O R

NH 2

R

Ph-OH

RCH 2OH RCH 2NH 2

RCOR

R

OH

R

Aldehyde RNO2

O

RCH 2 NH 2

Ph-OH

G

C

K

Ser

Met

Tyr

Valine

F

V

S

Ala

Lys

Gly

Methionine

A

M

Y

Cys

Phe

Val

Serine

Cys

Phe

Val

Serine

G

M

K

Met

Lys

Ala

Valine

Phenyl alanine

C

S

Y

Ser

Tyr

Gly

Methionine

Cysteine Lysine

F

A

V

Valine

Tyrosine Alanine

Serine Cysteine

Tyrosine Alanine

Phenyl alanine

Lysine Glycine Methionine

Glycine

Phenyl alanine Tyrosine Lysine

Alanine Cysteine

Glycine

K

Y

M

G

S

C

Lys

Val

Met

F

V

A

Tyr

Cys

Ser

Ala

Gly

Phe

1

Alanine

A

Ala

6 Methionine

M

Met

2

Cysteine

C

Cys

7 Serine

S

Ser

8 Valine

V

Val

9 Tyrosine

Y

Tyr

3 4 5

Phenylalanine

F

Phe

Glycine

G

Gly

Lysine

L

Lys

R

D

W

Glu

His

Gln

Isoleucine Asparagine Threonine

T

H

Q

Trp

Ile

Asn

Glutamic Acid

I

E

N

Thr

Asp

Arg

Gln

Asn

Asp

Arginine

His

Trp

Thr

Glutamine

Glu

Arg

Ile

Histidine

Asparagine

Arginine

Tryptophan Glutamine Histidine

H

E

W

Aspartic Acid

R

I

N

Tryptophan

Q

T

D

Threonine Isoleucine

Glutamic Acid

Aspartic Acid

Aspartic Glutamic Threonine Acid Acid

I

R

H

Asn

Trp

Gln

Glutamine

Histidine

D

W

E

Thr

Arg

Ile

Tryptophan Isoleucine Arginine

N

Q

T

Asp

His

Glu

Asparagine

1 Arginine 2 Asparagine 3 Aspartic Acid 4 Threonine 5 Tryptophan

Arg R Asn N Asp D Thr T Trp W

Gln Q 6 Glutamine 7 Glutamic Acid Glu E 8 Histidine His H 9 Isoleucine Ile I

-CH(Me) 2

-CH 2 Ph

-CH(Me)Et

3 4

Alanine Cysteine Phenyl alanine

Cys

Ile

Alanine

Glycine

Phenyl alanine

-Me

-H

Asp

Val

Leu

Serine

Cysteine

Isoleucine

-CH 2 SH

-CH 2OH

Phe

Gly

Ala

Leucine

Aspartic Acid

Valine

Ala

Ser

Ile

Leucine

Phenyl alanine

Glycine

Leu

Asp

Val

Cysteine

Isoleucine

Serine

Cys

Gly

Phe

Valine

Alanine

Aspartic -CH(Me)Et Acid

Aspartic Acid

Phenyl alanine

Alanine

-H

-CH 2iPr

-CH 2 SH

Serine

Valine

Leucine -CH(Me)Et

Glycine

1 2

Ser

-CH 2iPr -CH CO H 2 2

Isoleucine Cysteine

A C F

Ala

Cys Phe

-CH 2CO 2H

-Me

-CH 2OH

-CH 2CO 2 H -CH(Me) 2

-H

-CH 2SH

-CH 2 Ph

-Me

-CH 2 OH

-CH 2iPr

Val

Ile

Ser

-CH 2 Ph

Cys

Ala

Gly

-CH(Me) 2

Phe

Leu

Asp

-Me

R

-CH 2 SH -CH 2 Ph

Leucine

L

Leu

-CH 2 iPr

5

Aspartic Acid

D

Asp

-CH 2 CO 2H

6

Glycine

G

Gly

7

Serine

S

Ser

8

Valine

V

Val

-CH(Me)2

9

Isoleucine

I

Ile

-CH(Me)Et

-H -CH 2 OH

H3 N

COO

Amine

Phenol

Nitro

RCONH 2

RCOOR

Alcohol

Acid

Amide

RCOR

RNO2

Ester

RCOOH

Aldehyde Ketone

Ph-OH

RCOOH

RCONH 2

RCOR

RCOOR

RCHO

O R

O N

NH 2 R

R

O R

OR

OH R

R

O

OR R

R

OH

1 2 3

R

RCHO

Acid

RCOOH

Alcohol

RCH 2 OH

4

Phenol

5

Ketone

Amine

OH

6

Ester

RCOOR

Amide

RCONH 2

8

Nitro

RNO2

9

Amine

7

RCH 2NH 2

O

NH 2

R

Nitro

R

R O

O R

H

R

O

OR O

OH R

OH

NH 2 R

Aldehyde Phenol

N

O

Ketone

Ester

Acid

Amine

Nitro

Alcohol

Amide

RCOR

RCOOR

RCHO

Amide

Ester

RCH 2OH

RCH 2 NH 2

RCOOH

H

O OH

O

R R

OR

NH 2

O R

NH 2

NH 2

R

Ph-OH

O

R

R

R

RNO2

OH

R

OH

RCONH 2

OH

O

R

Acid

R

R

O

Ketone

O

R

R

Phenol Alcohol

NH 2 Aldehyde

Ph-OH RCOR

N

H R

O

H

Aldehido

NH 2 O

R

OH R

O R

OH R O

OH R

O

O

R

O O

Ph-OH

RCH 2OH RCH 2NH 2

O

RCH 2NH 2 RCH 2 OH

RNO2

O

RCHO

N

O