sulfadoxine- pyrimethamine, SP+PQ

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Plasmodium falciparum-endemic populations: a systematic review and meta- analysis. J Infect Dis 2009, 200: 1509-1517. 9. Mharakurwa S, Daniels R, Scott A, ...
Efficacy and safety of intermittent preventive treatment with Sulfadoxine–Pyrimethamine (SP) and SP- Piperaquine in schoolchildren in Democratic Republic of the Congo Junior R. Matangila 1,2, Joachim Yorokpa Doua2, Patrick Mitashi 1, Raquel Inocêncio da luz2, Pascal Lutumba1 and Jean-Pierre Van Geertruyden2 1Département de Médecine Tropicale, Université de Kinshasa, Kinshasa, République Démocratique du Congo Global Health Institute, University of Antwerp, Belgium

Introduction • Asymptomatic malaria infections cause anemia, malnutrition and reduces cognitive abilities in schoolchildren. • There is growing awareness of the importance of reducing the burden of malaria in school children and increasing political support for school-based malaria control • A couple of strategies have been suggested to fight malaria in this specific group . • Intermittent preventive treatment (IPT) may be a suitable strategy to prevent malaria and its adverse effects in schoolchildren. • However, little evidence is available and the most appropriate drug regimen for IPT still needs to be identified

Methods

Results •

Conclusions

616 children were enrolled in the trial.

• 410 (67%) were examined in the post-intervention. • Time had a significant effect on Hb level in all treatment arms[Control (p

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