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Suppl figures Oncogene (Final ppt 06 Mar2015) - Nature
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Suppl figures Oncogene (Final ppt 06 Mar2015) - Nature
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p75. i.p w/ PDLIM1 Ab input. kDa.
CTF
full-length. 19. PDLIM1. 25. ICD. i.b w/ PDLIM1 Ab. Supplementary figure S7. kDa p75. PDLIM1 actin input. i.p w/ p75 Ab.
Migratory Index (% of untreated Control)
Supplementary figure S1
140 120 100 80 60 40
*!
20
**!
0 U87R
U87R + Chol Ox
U87R ++! U87R M-β-CD! M-b-CD
MESF/ABC (X103)!
Supplementary figure S2
1000! 900! 800! 700! 600! 500! 400! 300! 200! 100! 0!
**! *!
pcDNA!
p75!
S303G!
Supplementary figure S3
BDNF (pg/ml)!
2500!
Cell lysates!
Supernantants!
*!
2000!
**!
1500! 1000! 500! 0! pcDNA!
p75!
S303G!
Supplementary figure S4
1800!
**!
MESF/ABC (X103)!
1600! 1400!
***!
1200! 1000!
*!
800! 600! 400! 200! 0! pcDNA
p75
SPV ΔSPV!
SPM
Supplementary figure S5
Cell lysates 1600
*!
1400 BDNF (pg/ml)!
Supernatant
1200
***! **!
1000 800 600 400 200 0 pcDNA!
p75!
ΔSPV
SPM!
Supplementary figure S6
Supplementary figure S7
i.p w/ p75 Ab !
input!
i.p w/ PDLIM1 Ab!
input!
kDa! p75!
kDa!
PDLIM1! i.b w/ p75 Ab
75!
full-length!
actin! p75!
75!
full-length!
25! 19!
i.b w/ PDLIM1 Ab
25!
CTF!
CTF! ICD!
actin! PDLIM1!
Supplementary figure S8
i.p w/ PDLIM1 Ab !
input!
i.p w/ PDLIM1 Ab!
kDa!
kDa! p75! 75!
25! 19! i.b w/ PDLIM1 Ab
full-length!
input!
p75!
75!
full-length!
25!
CTF!
CTF! ICD! actin! PDLIM1!
i.b w/ PDLIM1 Ab
actin! PDLIM1!
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