SUPPLEMENTAL MATERIAL Table S1. Transcript expression profile ...
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SUPPLEMENTAL MATERIAL Table S1. Transcript expression profile ...
SUPPLEMENTAL MATERIAL Table S1. Transcript expression profile for potential mechanisms in the cav-1 KO mice (values normalized to 18S mRNA)
Variable
WT [n=16]
Cav-1 KO [n=16] p-value
Resistin (fat)
1.00 ± 0.10
2.09 ± 0.244
< 0.001
Resistin (liver)
1.00 ± 0.17
3.37 ± 0.92
0.008
RBP4 (fat)
1.00 ± 0.13
2.10 ± 0.41
< 0.001
RBP4 (liver)
1.00 ± 0.07
1.74 ± 0.40
0.014
G6PD (fat)
1.00 ± 0.09
1.84 ± 0.38
0.008
G6PD (liver)
1.00 ± 0.10
2.45 ± 0.50
< 0.001
NOX4 (fat)
1.00 ± 0.10
1.80 ± 0.33
0.008
NOX4 (liver)
1.00 ± 0.21
0.69 ± 0.31
0.395
AldoR (fat)
1.00 ± 0.09
1.38 ± 0.14
0.026
AldoR (liver)
1.00 ± 0.11
0.75 ± 0.10
0.149
Figure S1. Adipose tissue cav-1 expression by rs926198 genotype (Genevar database). The minor allele C has a dose-dependent, decreasing effect on cav-1 transcript levels in tissue from the MuTHER Pilot study, p
