Supplemental Table 2: Genomic regions putatively involved in ... - PLOS

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13.3 106920- 120228. Multidrug efflux proteins; exodeoxyribonuclease III. (similarity to Natamycin biosynthetic gene cluster). -. AS-3. A. 62. 6.1. 182853- 188920.
Supplemental Table 2: Genomic regions putatively involved in antibiotic and secondary metabolite production for Rathayibacter toxicus FH-79 and identified with the data-mining software antiSMASH v. 3.0 (Weber et al. 2015). Regions of interest AS-1 AS-2 AS-2

Putative gene cluster A B

% GC 61 58 63

Size (kb) 14.4 11 13.3

Coordinates

Putative gene(s) of interest

54051- 68462 85535- 96547 106920- 120228

AS-3 AS-3 AS-3 AS-4 AS-5 AS-6

A B C A

62 64 54 64 65 61

6.1 11.2 13.8 9.4 12.2 5.7

182853- 188920 200753- 211986 217546- 231327 318313- 327700 372485- 384693 411139- 416791

AS-6 AS-7 AS-8 AS-9 AS-10

B A

57 60 63 63 72

9.4 7.6 28.7 7.4 11.9

435885- 445293 470870- 478475 582536- 611266 696648- 704027 736861- 748754

AS-10 AS-11 AS-12 AS-12 AS-12 AS-13 AS-13 AS-14 AS-15 AS-15

B A B C A B A B

59 61 52 62 57 61 62 55 60 63

8.5 19.2 13.4 14.4 5.2 12.1 21.4 16.2 8.3 7.7

754719- 763195 790328- 809488 905229- 918630 924102- 938484 941897- 947133 1086846- 1098917 1102200- 1123610 1252302- 1268522 1349072- 1357411 1359348- 1367067

Glycosyltransferases; phosphatases; multidrug efflux proteins Metalloprotease; multidrug efflux proteins Multidrug efflux proteins; exodeoxyribonuclease III (similarity to Natamycin biosynthetic gene cluster) Type III polyketide synthase Amino acid permeases; glycosyltransferases YD/RHS-like repeat associated proteins Peptide synthase; 3-oxoacyl-ACP synthase III Menaquinone biosynthetic cluster Amino acid permease; two-component system proteins (similarity to clavulanic acid biosynthetic gene cluster) Transglycosylase exopolysaccharide biosynthesis- related genes Wcq-like exopolysaccharide biosynthetic gene cluster Aminotransferases; enoylreductase (polyketide synthesis) Non-ribosomal peptide synthetase; multidrug efflux proteins; peptidase ABC transporters Glycosyltransferases; methyltransferase Tunicamycin-like genes Non-ribosomal peptide synthetase; multidrug efflux proteins ChpD Multidrug efflux proteins; lantibiotic cyclase; transposase beta-ketoacyl-ACP reductase; glycosyltransferases Multidrug efflux proteins; acyl transferases Multidrug efflux proteins; patatin-like phospholipase Acyl-carrier proteins; PucR family transcriptional regulator

AlienHunter overlap AH-1 AH-2 AH-4 AH-7 AH-12 AH-13 AH-16 AH-17 AH-19 AH-20 AH-21 -

AS-15 AS-16

C A

58 59

9.3 11.9

1374127- 1383439 1608300-1620201

AS-16 AS-16

B C

64 59

18.2 9.6

1623809-1642017 1645206- 1654758

AS-17 AS-17 AS-17 AS-18

A B C A

67 54 63 59

11.5 6.3 16.3 9.2

1768456- 1779983 1789681-1795938 1796651- 1812920 2031332- 2040560

AS-18

B

58

11.3

2044513-2055855

AS-18 AS-18

C D

64 62

12.9 7.6

2065102- 2077962 2087211- 2094820

AS-19 AS-20

-

53 54

12.3 7.7

2239582-2251891 2308630-2316348

Bacterial lysin (BacA-like); Multidrug efflux proteins Type VII secretion proteins; DNA/RNA non-specific endonuclease LPS heptosyltransferase; glycosyltransferases YD-like repeat and RHS repeat-associated core domaincontaining proteins; bacterial EndoU nuclease ChpF; glycosyltransferase putative AbiEii toxin polyketide cyclase Serine proteases (ChpG, ChpK, ChpH); Endonuclease/Exonuclease/phosphatase family-like protein ATP-grasp domain-containing proteins; phosphoenolpyruvate mutase (similarity to Rhizocticin biosynthetic gene cluster) Lantibiotic: bacteriocin biosynthesis cluster Antibiotic biosynthesis monooxygenase; multidrug efflux protein; CheY-like REC domain-containing protein Multidrug efflux proteins; glycosyltransferases Multidrug efflux proteins

AH-22 AH-26 AH-27 AH-28 AH-29 AH-30 AH-34 AH-35 AH-39 AH-41