Supplementary Figure 2A

Supplementary Figure 2A

Gb3[(d18:1)(C24:0)] 10.4 min

Counts per second CPS: 8.93E+03

Gb3[(d18:1)(C24:0)] 10.0 min Gb3[(d18:1)(C24:2)] + Gb3[(d18:2)(C24:1)] 9.8 min

Gb3[(d18:1)(C16:0)] 8.7 min

Gb3[(d18:1)(C20:0)] 9.6 min

Gb3[(d18:1)(C24:1)] + Gb3[(d18:2)(C24:0)] 10.1 min

Gb3[(d18:1)(C22:0)] Me 10.2 min

Gb3[(d18:1)(C18:0)D3] 9.2 min Gb3[(d18:1)(C18:0)] 9.2 min Gb3[(d18:1)(C24:0)] Me 10.5 min

Gb3[(d18:1)(C26:0)] 10.7 min

B Heart

Internal std

Kidney

Monohexosylceramide (d18:1 24:1)

Lung

Spleen

Brain

Liver

Monohexosylceramide (d18:1 8:0)

C

Heart

Internal std

Kidney

Dihexosylcer (d18:1 16:0) d3

Dihexosylcer (d18:1 18:0)

Lung

Spleen

Brain

Liver

D Heart

Kidney

Liver

Lung

Spleen

Brain

Internal std Ceramide (d18:1 24:0)

Ceramide (d18:1 22:0) d4

E Brain

Liver

Brain

Brain

GM2(d18:1 16:0)

GM2(d18:1 18:0)

GM2(d18:1 18:0)

GM2(d18:1 18:1)

Internal std

GM3(d18:1 18:0) d3

GM3(d18:1 18:0) d3

GM3(d18:1 18:0) d3