Volatile Organic Compounds in Exhaled Breath from Lung Cancer Patients Using Support Vector. Machine Algorithm. Yuichi Sakumura, Yutaro Koyama, HiroakiĀ ...
Sensors 2017, 17, doi:10.3390/s17020287; 287
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Supplementary Materials: Diagnosis by Volatile Organic Compounds in Exhaled Breath from Lung Cancer Patients Using Support Vector Machine Algorithm Yuichi Sakumura, Yutaro Koyama, Hiroaki Tokutake, Toyoaki Hida, Kazuo Sato, Toshio Itoh, Takafumi Akamatsu and Woosuck Shin Butane
0.6
0.3 0.2
0.25
0.25
Probability
Probability
Probability
0.4
0.2 0.15 0.1
0.1 0.2
0.4
0.6
0.8
0
1
0
50
100
ppb)
C8H16
0.05 5
0.3 0.2
0
10
0
0.1
0.2
20
0.3 0.2
0.3 0.2
0
0.6
0.2 0.15 0.1 0.05
0
0.5
1
1.5
ppb)
2
2.5
0
0
2
4
ppb)
(g)
8
(i)
Unknown
0.5
0.25
6
ppb)
(h)
Nonanal
80
0.25
0.1 0.4
60
Toluene
0.3
Probability
0.4
0.2
40
(f)
0.4
Probability
Probability
0
ppb)
Methylcyclohexane
0.5
0.1
0.4
Probability
Probability
0
0.3
(e)
0.5
0.2 0.15 0.1
0.3 0.2 0.1
0.05 0
0.1
ppb)
(d)
0.3
0.2 0.15
0.05
ppb)
Xylene
6
0.25
0.1
0
4
C8H17OH
0.3
Probability
Probability
Probability
0.1
0.6
2
(c)
0.4
0
0
ppb)
Dichlorobenzene
0.5
0.15
0
0
150
(b)
0.2
0
0.1
ppb)
(a) 0.25
0.2 0.15
0.05
0.05 0
2-Propanol
0.3
0.3
0.5
0
Acetone
0.35
0
1
2
3
0
0
5
10
ppb)
(j)
15
ppb)
(k)
Figure S1. VOC concentration distributions from lung cancer (red, n = 107) and healthy (green, n = 29) controlsā breath; (a) butane; (b) acetone; (c) 2-propanol; (d) C8H16; (e) dichlorobenzene; (f) C8H17OH; (g) xylene; (h) methylcyclohexane; (i) tolunene; (j) nonanal; and (k) unknown compound.