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Acute lymphoblastic leukaemia (ALL) is the maximum common pediatric leukemia accounting for 25-30% of all cases of childhood malignancies (Krajinovic et ...
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Belatacept-Based Immunosuppressive Therapy: ... Belatacept has been associated with an increased acute rejection rate after kidney transplantation. This case ...
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Nov 6, 2011 - Influence of CYP2B6 516G>T polymorphism and interoccasion variability (IOV) on the population pharmacokinetics of efavirenz in HIV-infected.
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Aug 19, 2013 - An-qiang Zhang, Cai-li Yue, Wei Gu, Juan Du, Hai-yan Wang, Jianxin Jiang* ... Citation: Zhang A-q, Yue C-l, Gu W, Du J, Wang H-y, et al.
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Background: Matrix metalloproteinase-2 (MMP-2) is an enzyme with ... our Saudi population and the MMP-2 gene expression level was found to be 10 times ...
different between PCOS group and control group in different gene models (For AA + ... Keywords: Polycystic ovary syndrome, FTO, Meta-analysis, Polymorphism.
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International Journal of Organ Transplantation Medicine. Original Article ..... Kaczor MP, SeczyÅska M, Szczeklik W, Sanak M. IL28B polymorphism (rs12979860) ...
Original Article Interleukin-28B rs12979860 C/T Polymorphism and Acute Cellular Rejection after Liver Transplantation H. Fereidooni1, N. Azarpira2*, R. Yaghobi2, A. Vahdati3, S. A. Malek-Hoseini2,4
Department of Physiology, Fars Science and Research Branch, Islamic Azad University, Shiraz, Iran 2 Transplant Research Center, Stem Cell Research Institute, Shiraz University of Medical Sciences, Shiraz, Iran 3 Department of Physiology, Shiraz Branch, Islamic Azad University, Shiraz, Iran 4 Transplant Center, Shiraz University of Medical Sciences, Shiraz, Iran 1
ABSTRACT Background: Interleukin-28 (IL-28B) rs12979860 C/T polymorphism is a known predictor of sustained virological response after antiviral treatment in hepatitis C. IL-28B affects the innate immune system as well as intrahepatic expression level of interferon-stimulated genes. Objective: To investigate the effect of recipient IL-28B polymorphism on occurrence of acute rejection after liver transplantation.
Methods: 140 liver allograft recipients were selected. Acute rejection episodes were recorded in 39 patients (AR group); the remaining had normal graft function (non-AR group). 70 normal subjects were also studied as the control group. The IL-28B rs12979860 was genotyped through PCR-RFLP method.
Results: No significant difference was found between AR and non-AR groups in terms of genotype and allele frequency. However, the CC genotype was significantly (p