ATCC. See ref. Gazdar et al, 1998. HCC1419. Breast. ATCC. See ref. Gazdar et al ... ATCC. DMEM/F12 Fogh and Trempe 1975. SUM159. Breast. Orig. See ref.
Table 1: Cancer cell lines used Cell Line BT-20 BT-474 CaMa-1 DU4475 HCC1143 HCC1187 HCC1419 HCC1500 HCC1569 HCC1599 HCC1806 1 HCC1937 HCC1954 HCC38 HCC70 HS578t MCF-7 MDA-MB-134 MDA-MB-175 MDA-MB-361 MDA-MB-415 MDA-MB-453 MDA-MB-468 PMC42 SKBR-3 SUM159 SUM44 SUM52 T47D UACC812 ZR-75-1 ZR-75-30 Caov-3 PA-1 SK-OV-3 2 Capan-1 CF-PAC-1 MIA PaCa-2 PancTu1 RWP-1 Suit2
1 2
Tissue Breast Breast Breast Breast Breast Breast Breast Breast Breast Breast Breast Breast Breast Breast Breast Breast Breast Breast Breast Breast Breast Breast Breast Breast Breast Breast Breast Breast Breast Breast Breast Breast Ovarian Ovarian Ovarian Pancreatic Pancreatic Pancreatic Pancreatic Pancreatic Pancreatic
3
Source O’Hare O’Hare Chaffanet O’Hare ATCC ATCC ATCC ATCC ATCC ATCC ATCC ATCC ATCC ATCC ATCC O'Hare ATCC O'Hare O'Hare ATCC O'Hare ATCC O’Hare O'Hare ATCC Orig Orig Orig ATCC Sanger ATCC O’Hare Brenton Brenton O’Hare ATCC Lemoine Lemoine Lemoine Lemoine Lemoine
This cell line is a BRCA1 mutant This cell line is a BRCA2 mutant
4
Medium DMEM/F12 DMEM/F12 RPMI-1640 RPMI-1640 See ref See ref See ref See ref See ref See ref See ref See ref See ref See ref See ref DMEM/F12 DMEM/F12 DMEM/F12 DMEM/F12 DMEM/F12 DMEM/F12 DMEM/F12 DMEM/F12 DMEM/F12 DMEM/F12 See ref See ref See ref DMEM/F12 DMEM/F12 DMEM/F12 RPMI-1640 DMEM/F12 DMEM/F12 McCoy’s RPMI-1640 RPMI-1640 DMEM/F12 RPMI-1640 RPMI-1640 RPMI-1640
Reference Lasfargues et al, 1958 Lasfargues et al, 1978 Dobrynin et al, 1963 Langlois et al., 1979 Gazdar et al, 1998 Gazdar et al, 1998 Gazdar et al, 1998 Gazdar et al, 1998 Gazdar et al, 1998 Gazdar et al, 1998 Gazdar et al, 1998 Gazdar et al, 1998 Gazdar et al, 1998 Gazdar et al, 1998 Gazdar et al, 1998 Hackett et al, 1977 Soule, et al. 1973 Cailleau, et al. 1974 Cailleau, et al. 1974 Satya-Prakash, et al. 1981 Cailleau et al, 1978 Cailleau et al, 1978 Cailleau, et al. 1978 Whitehead, et al. 1983 Fogh and Trempe 1975 Flanagan et al, 1999 Mahacek et al, 1993 Ethier et al, 1996 Keydar, et al. 1979 Meltzer et al, 1991 Engel et al, 1978 Engel et al, 1978 Zeuthen et al., 1980 Fogh et al, 1977 Fogh et al, 1977 Schoumacher, et al. 1990 Yunis et al., 1977 Moore, et al. 2001 Dexter, et al. 1982 Iwamura, et al. 1987
3
ATCC, American Type Culture Collection, in most cases via the European Collection of Animal Cell Cultures (ECACC, Porton Down, UK) Brenton, Dr James Brenton, CRUK CRI, Li Ka Shing Centre, Cambridge, UK Chaffanet, Dr Max Chaffanet (Departement d’Oncologie Moleculaire, Institute Paoli Calmettes, Marseille) Lemoine, Prof Nicholas R Lemoine (Centre for Molecular Oncology, Institute of Cancer and the Cancer Research UK Clinical Centre, Barts and The London School of Medicine, London, UK) O’Hare, Prof Michael J. O'Hare (LICR/UCL Breast Cancer Laboratory, University College, Middlesex Medical School, London, UK) Orig, from the originator Sanger, from The Sanger Institute, Hinxton, UK 4 Media abbreviations: DMEM/F12 - Dulbecco's Modified Eagle Media:F12 nutrient mixture, RPMI-1640 Roswell Park Memorial Institute Medium 1640
