Eur Radiol (2009) 19: 966–974 DOI 10.1007/s00330-008-1225-1
Aleksander Falkowski Wojciech Poncyljusz Grażyna Wilk Małgorzata Szczerbo-Trojanowska
Received: 3 June 2008 Revised: 30 September 2008 Accepted: 3 October 2008 Published online: 26 November 2008 # European Society of Radiology 2008 A. Falkowski (*) . G. Wilk Departament of General and Dental Diagnostic Imaging, Pomeranian Medical University of Szczecin, Al. Pow. Wielkopolskich 72, 70–111 Szczecin, Poland e-mail:
[email protected] Tel.: +048-91-4661174 Fax: +048-91-4661175 W. Poncyljusz Departament of Diagnostic Imaging and Interventional Radiology, Pomeranian Medical University of Szczecin, Uni Lubelskiej 1, 71–252 Szczecin, Poland M. Szczerbo-Trojanowska Department of Interventional Radiology and Neuroradiology, Medical University of Lublin, Jaczewskiego 8, 20–954 Lublin, Poland
VASCU LAR- INTERVEN TIONAL
The evaluation of primary stenting of sirolimus-eluting versus bare-metal stents in the treatment of atherosclerotic lesions of crural arteries
Abstract A comparison was made of sirolimus–eluting stents and bare stents as an effective means of treatment of stenosis in crural arteries. Patients were randomly divided into two groups: (1) patients treated with sirolimus-eluting stents and (2) patients treated with bare stents. Each group consisted of 25 patients, and every patient had one stent implanted. All patients showed symptoms of ischemia of the peripheral arteries, classified according to the Rutherford scale into categories 3, 4, and 5. All patients were examined 24 h before and 24 h and 6 months after the intervention. The results were analyzed according to clinical, hemodynamic, and angiographic criteria. Technically, the procedure was successful in 100% of cases, and both groups presented an equal improvement in clinical and hemodynamic parameters. The follow-up angiographic examination demonstrated a
Introduction In chronic ischemia of the lower limbs, about 70% of hemodynamically and clinically significant atherosclerotic lesions are found in segments below the inguinal ligament. Lesions of the crural arteries occurred in about 15% of patients, but combined with femoral-popliteal lesions, this percentage increased to about 30% [1]. It is estimated that critical limb ischemia (CLI) develops in 15% to 30% of patients with chronic ischemia of the lower limbs in the
significantly lower rate of restenosis among the sirolimus-eluting stent group (4, 16%) versus the bare stent group (19, 76%) (p
