Mar 20, 2018 - relationship of LA dimension (LAD), indexed volume (LAVI max, LAVI min), (peak atrial longitudinal (PALS) and contraction (PACS) strain.
911 JACC March 20, 2018 Volume 71, Issue 11
Heart Failure and Cardiomyopathies THE RELATIONSHIP BETWEEN LEFT ATRIAL MEASUREMENTS AND CAVITY PRESSURE: A SYSTEMATIC REVIEW AND META-ANALYSIS Poster Contributions Poster Hall, Hall A/B Sunday, March 11, 2018, 3:45 p.m.-4:30 p.m. Session Title: Cardiomyopathies: Assessment and Outcomes Abstract Category: 13. Heart Failure and Cardiomyopathies: Clinical Presentation Number: 1238-096 Authors: Ibadete Bytyci, Gani Bajraktari, Pranvera Ibrahimi, Per Lindqvist, Michael Henein, Clinic of Cardiology, Prishtina, Albania, Umea University, Umea, Sweden Background: Pulmonary capillary wedge pressure (PCWP), is used as a measure of left atrial pressure (LAP), in order to avoid the risk of trans-septal puncture. The aim of this meta-analysis was to assess the correlation between LA size, function and PCWP. Methods: PubMed-Medline, EMBASE, Scopus, Google Scholar and the Cochrane Central Registry were searched for studies of the relationship of LA dimension (LAD), indexed volume (LAVI max, LAVI min), (peak atrial longitudinal (PALS) and contraction (PACS) strain and total emptying fraction (LAEF) and PCWP. Eighteen articles with 1221 patients were included. Results: The pooled analysis showed association between PCWP and LAD: Cohen’s d=0.96, LAVI max: d =0.98, and LAVI min: d =1.0 (p=0.0001 for all). A stronger correlation was found between PCWP and PALS: d = 1.35, PACS: d =1.62, total EF d =1.22 (p20cm2 (AUC: 0.80), LAEF 35% (0.80), PALS 19% (0.78), and LAVI max>33 ml/m2 (0.78). Conclusion: Increased LA size and reduced myocardial function predict raised cavity pressure. These results should assist in optimum follow up of patients with fluctuating LA pressure.
