The Risk Factors and Causes for Blindness in ...

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Behcet's disease is a chronic inflammatory disease with remissions and exacerbations. It is a vasculitis causing obliteration, and fibrinoid necrosis of the veins ...
Blindness and Behcet's Disease • Chams et al

Iranian Journal of Ophthalmology • Volume 20 • Number 2 • 2008

The Risk Factors and Causes for Blindness in Behcet’s Disease Hormoz Chams, MD1 • Alireza Lashay, MD1 • Ahmad Javadian, MD1 Reza Karkhaneh, MD1 • Farhad Shahram, MD2 • Fereidoun Davatchi, MD3 Abstract Purpose: To investigate the risk factors and causes for blindness in Behcet’s disease (BD). Methods: In this preliminary retrospective case series we have investigated 27 BD patients (54 eyes), legally blind (vision 0.1 or less) at least in one eye at the last visit (2006), and compared them with 54 eyes of 27 non-blind patients (control group), matched individually and consequently in terms of duration of BD follow-up and treatment. Results: Eighteen (66.6%) of our blind patients were male versus thirteen (48%) of the control group (p=0.167). Low vision (0.1 or less) at the first consultation, 23 eyes (42.6%) in the blind group versus three eyes (5.6%) in the control group (p=0.001), higher number of uveitis in the main group 51 eyes (94.4%) versus 35 eyes (64.8%) in the control group (p=0.007), Longer duration of uveitis (10.3±4.8 vs. 5.1±3.97years, p

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